Actos (pioglitazone) Coupons, Discounts & Cost
Actos (pioglitazone) is a hypoglycemic drug for oral administration. One way to save money on the Actos (pioglitazone) retail cost regardless of income and insurance status is to use Actos (pioglitazone) coupons or discount cards from RXCoupons. Use our Actos (pioglitazone) coupons at your online pharmacy and receive up to 75% off the sale price each time you refill your prescription.
Actos (pioglitazone) - general information and indications for use
Actos (pioglitazone) is a hypoglycemic drug for oral administration. It is indicated for the treatment of patients with type 2 diabetes - either as monotherapy or in combination with other agents. It is also used as an adjunct to diet therapy and physical training. Actos (pioglitazone) is able to reduce insulin resistance of the peripheral tissues and liver, resulting in activation of glucose disposal. It improves glycemic control in patients with type 2 diabetes and lowers the plasma insulin concentration.
How to take Actos (pioglitazone)
Actos (pioglitazone) is prescribed 1 time a day regardless of the meal. In monotherapy in patients with diabetes who do not achieve the desired goals of treatment with the help of diet therapy and exercise, Actos (pioglitazone) is prescribed at a dose of 15 mg or 30 mg once daily. The dose can be gradually increased up to 45 mg/day, if necessary. The maximum dose of the drug in monotherapy is 45 mg 1 time a day. If monotherapy is ineffective, it can be replaced with combination therapy. The maximum dose of Actos (pioglitazone) in combination therapy is 30 mg/day.
When Actos (pioglitazone) is contraindicated
Actos (pioglitazone) is contraindicated in patients with: - Type 1 diabetes - Hypersensitivity - Diabetic ketoacidosis - Severe heart failure - During pregnancy, lactation.
Actos (pioglitazone) may be administered with caution in hydropic syndrome, anemia, liver and heart failure.
High-risk patients and possible side effects
Actos (pioglitazone) in combination with other hypoglycemic drugs and insulin may cause hypoglycemia, edema, weight gain. In addition, rare effects may include headaches, sinusitis, myalgia, pharyngitis, anemia, congestive heart failure, as well as decrease in hemoglobin and hematocrit levels. In rare cases, other disorders can occur, including increased liver enzymes. The activity of liver enzymes should be investigated before initiating treatment and periodically during treatment. In case of hepatic failure, jaundice or symptoms of liver dysfunction (unexplained nausea, vomiting, abdominal pain, weakness, anorexia, dark urine) the therapy should be stopped immediately.
In case of overdose
Actos (pioglitazone) monotherapy is not accompanied by specific symptoms in case of overdose. Actos (pioglitazone) in combination therapy may cause symptoms of hypoglycemia.
Drug-drug interaction studies
The effect of Actos (pioglitazone) appointment may be stronger with sulfonylurea agents or insulin. The combination of Actos (pioglitazone) and oral contraceptives can reduce the effectiveness of contraception. Co-administration of NSAIDs may cause fluid retention and edema.
Warning signs and symptoms
Actos (pioglitazone) reception for the treatment of type 2 diabetes must be accompanied by a diet therapy and physical exercise.
Before starting the therapy, it is necessary to instruct the patient about the possible occurrence of swelling, sudden weight gain or other changes that require immediate discontinuation of the drug and medical attention.
Actos (pioglitazone) therapy requires regular observation of cardiac, renal, and hepatic function. In case of serious violations Actos (pioglitazone) should be discontinued immediately and appropriate therapy instituted.
Patients receiving ketoconazole concurrently with Actos (pioglitazone) require regular glucose control.
How should I store Actos (pioglitazone)?
Store the drug at a temperature of 15-30° C in places protected from moisture and light. Think of your children's safety by keeping this medication out of their reach.