Antabuse (disulfiram) Coupons and Discounts
Antabuse (disulfiram) belongs to the class of drugs that are prescribed to treat alcohol dependence. One way to save money on the Antabuse (disulfiram) retail cost regardless of income and insurance status is to use Antabuse (disulfiram) coupons or discount cards from RXCoupons. Use our Antabuse (disulfiram) coupons at your online pharmacy and receive up to 75% off the sale price each time you refill your prescription.
What is Antabuse (disulfiram)?
Antabuse (disulfiram) belongs to the class of drugs that are prescribed to treat alcohol dependence. Disulfiram increases sensitivity to alcohol and stops the craving for alcohol.
When mixed with alcohol, Antabuse leads to increased concentrations of acetaldehyde, which causes negative feelings and toxic physical reactions (flushing, burning feeling on the face, chest tightness, shortness of breath, nausea, vomiting, tachycardia, anxiety, etc.).
When can I use Antabuse (disulfiram)?
Antabuse (disulfiram) is used for the treatment of chronic alcoholism and alcohol relapse prevention.
Antabuse (disulfiram) dosage
Antabuse (disulfiram) can be taken only under your doctor’s supervision. There are no generally accepted instructions for the dosage and duration of treatment.
To take Antabuse tablets, you should fully dissolve them in a glass of water.
The drug is taken at a dose of 200-500 mg 1-2 times per day. After 7-10 days, each patient has an alcohol-drug test reaction (for calculating your correction dose if necessary). You can then use a maintenance dose of 150-200 mg / day for 1-3 years.
Antabuse (disulfiram) side effects
Antabuse (disulfiram) may cause unwanted side effects such as metallic taste in the mouth, hepatitis, optic neuritis, memory loss, confusion, fatigue, headache, allergic reactions.
Disulfiram-ethanol reaction: respiratory failure, cardiovascular collapse, cardiac arrhythmias, angina pectoris, myocardial infarction, convulsions, neurological disorders, cerebral edema.
Disulfiram chronic administration: psychosis, hepatitis, gastritis, thrombosis, polyneuritis.
Antabuse (disulfiram) contraindications
Absolute contraindications: - Severe diseases of the cardiovascular system, neuritis of the auditory nerve, glaucoma, optic neuritis; - Asthma, emphysema; - Pulmonary tuberculosis; - Severe hepatic impairment; - Diabetes; - Hyperthyroidism; - Epilepsy and convulsions of any origin; - Mental illnesses; - Peptic ulcer disease; - Kidney disease; - Malignant tumors; - Polyneuritis; - Pregnancy and lactation; - Individual sensitivity to the drug.
Relative contraindications: - Cardiovascular diseases (stage of compensation); - Elderly patients (over 60 years); - Gastric ulcer and duodenal ulcer disease in remission.
The drug is contraindicated during pregnancy and lactation.
During the treatment, patients are advised to avoid drinking alcoholic beverages, or use cosmetic products that contain alcohol.
Do not drive or operate machinery if you are on Antabuse therapy.
Antabuse (disulfiram) special instructions
Patients should be warned of high alcohol sensitivity or even intolerance to alcohol.
Co-administration with oral anticoagulants is associated with an increased risk of bleeding.
Disulfiram should be taken with caution in patients with renal insufficiency or hypothyroidism, especially in combination with alcohol.
Antabuse (disulfiram) overdose
Disulfiram-ethanol combination can cause a state of consciousness very similar to coma, as well as cardiovascular collapse and neurological complications.
Antabuse (disulfiram) drug interactions
Contraindicated combinations: - Alcohol. Toxic reaction (flushing, erythema, vomiting, tachycardia). Avoid taking alcoholic drinks and medicines containing alcohol.
Undesirable combinations: Isoniazid. Such combination can lead to a variety of problems. 5-nitroimidazole drugs (metronidazole, ornidazole, secnidazole, tinidazole) can lead to delirious disorders, confusion. Phenytoin combination is associated with toxic symptoms.
Combinations requiring caution: Theophylline. Disulfiram inhibits the metabolism of theophylline. As a result, theophylline dose should be reduced. Warfarin (and other oral anticoagulants) may cause bleeding. Benzodiazepines. Disulfiram may potentiate the sedative effects of benzodiazepines (especially chlordiazepoxide and diazepam). Tricyclic antidepressants may cause potentially dangerous reactions, especially if the patients mix disulfiram with alcoholic drinks.