Arava (leflunomide) Coupons and Discounts
Arava (leflunomide) is a drug belonging to the class of antirheumatic agents with immunosuppressive, immunomodulatory, anti-proliferative and anti-inflammatory properties. One way to save money on the Arava (leflunomide) retail cost regardless of income and insurance status is to use Arava (leflunomide) coupons or discount cards from RXCoupons. Use our Arava (leflunomide) coupons at your online pharmacy and receive up to 75% off the sale price each time you refill your prescription.
What is Arava (leflunomide)?
Arava (leflunomide) is a drug belonging to the class of antirheumatic agents with immunosuppressive, immunomodulatory, anti-proliferative and anti-inflammatory properties.
What should you know about Arava (leflunomide) indications?
Arava (leflunomide) works well among those people with rheumatoid arthritis (as a basic drug for reducing symptoms of structural damage of joints) and active psoriatic arthritis.
What should you know about Arava (leflunomide) contraindications?
Absolute contraindications: severe immunodeficiency disorders (AIDS), abnormal liver function, severe infections, bone marrow suppression, severe leukopenia, neutropenia, anemia, thrombocytopenia, non-psoriatic and rheumatoid arthritis, severe hypoproteinemia (nephrotic syndrome), moderate and severe renal insufficiency, glucose-galactose malabsorption, lactase deficiency or galactose intolerance, pregnancy, age up to 18 years, lactation, combined therapy with teriflunomide, hypersensitivity to the drug.
Relative contraindications (use with extreme caution): age over 60 years, interstitial lung disease, diabetes, mild renal insufficiency, mild to moderate anemia, leucopenia, neutropenia, thrombocytopenia, bone marrow disorders, combined therapy with other drugs with immunosuppressive effect, combined therapy with other neurotoxic drugs.
Arava (leflunomide) dosage and administration
Patients should swallow the tablets whole and drink plenty of fluids. Food does not affect the effectiveness of the drug. The initial dose for early treatment is usually 100 mg (loading dose) 1 time per day for 3 days. Further, reduce the dose up to 20 mg 1 time per day or up to 10 mg in the case of poor tolerability. The therapeutic effect usually develops within four weeks.
What should you know about Arava (leflunomide) side effects?
Arava (leflunomide) side effects include: Digestive system: diarrhea, nausea, abdominal pain, stomatitis, anorexia, vomiting, hyperbilirubinemia, jaundice, cholestasis, hepatitis, pancreatitis, liver failure or acute liver necrosis. Cardiovascular system: high blood pressure. Nervous system: paresthesia, dizziness, headache, anxiety, peripheral neuropathy. Respiratory system: interstitial lung disease. Hematopoietic system: leukopenia, thrombocytopenia, anemia, eosinophilia, leukopenia, pancytopenia, agranulocytosis. Metabolism: weight loss, hypophosphatemia, mild hyperlipidemia, hypokalemia, hypouricemia. Infectious and parasitic diseases: severe infection and sepsis (can be fatal), rhinitis, bronchitis and pneumonia. Skin and subcutaneous tissue disorders: dry skin, itching, eczema, erythema multiforme, toxic epidermal necrolysis, psoriasis, pustular psoriasis, cutaneous lupus erythematosus. Allergic reactions: rash, urticaria, vasculitis, anaphylactic reactions, fatigue.
What should you know about Arava (leflunomide) special instructions?
Before starting treatment with Arava (leflunomide), be aware of a possible increase in the number of side effects in patients previously treated with other agents for the treatment of rheumatoid arthritis.
Arava should be used only after a thorough medical examination. The drug is contraindicated in pregnant women and women of childbearing age who are planning pregnancy or are unable to use reliable methods of contraception.
Men also should be warned about the possible adverse effects of leflunomide. You need to monitor liver function tests before the therapy and regularly while taking Arava (1-2 times a month during the first 6 months, then every 6-8 weeks). More frequent monitoring is required in the following cases: simultaneous or previous use of immunosuppressive drugs, signs of blood abnormalities.
Before the therapy, all patients should be tested for tuberculosis. It is not recommended to use live vaccines during Arava treatment. It is recommended to refrain from driving a vehicle during the whole period of treatment. Do not drink alcohol while on Arava treatment.
You should be careful when using phenytoin, warfarin, tolbutamide (except NSAIDs).