Artane (trihexyphenidyl) Coupons, Discounts & Cost
Artane (trihexyphenidyl) is an antispasmodic drug for the treatment of Parkinson's disease. One way to save money on the Artane (trihexyphenidyl) retail cost regardless of income and insurance status is to use Artane (trihexyphenidyl) coupons or discount cards from RXCoupons. Use our Artane (trihexyphenidyl) coupons at your online pharmacy and receive up to 75% off the sale price each time you refill your prescription.
Artane (trihexyphenidyl) pharmacologic effect
Artane (trihexyphenidyl) is an antispasmodic drug for the treatment of Parkinson's disease. It effectively treats extrapyramidal symptoms associated with treatment with neuroleptics (torsion dystonia, orofacial dyskinesia, Oculogyric crisis, akathisia).
Artane has inflammatory properties. It inhibits parasympathetic nervous system activity and relaxes smooth muscles.
Artane (trihexyphenidyl) indications
Artane (trihexyphenidyl) is used to treat Parkinson's disease, all forms of parkinsonism and other lesions in the extrapyramidal tract: spastic paralysis of central origin, and others.
Artane is also used for the treatment of depression syndrome and reduced mental capacity.
Artane does not contribute to the development of glaucoma. Therefore, it is particularly effective for the treatment of atherosclerotic parkinsonism.
Artane (trihexyphenidyl) dosage and administration
Artane (trihexyphenidyl) is taken during or after a meal, starting with a dose of 1 mg per day. The dosage may be increased to 2-4 mg (in 3-4 divided doses) depending on individual tolerability. It is desirable to take Artane with food (to avoid nausea).
Patients receiving other medicines should slightly reduce the dose of other medications.
The highest single dose of Artane is 10 mg. The highest daily dose is 20 mg.
What are the side effects for Artane (trihexyphenidyl)?
Adverse events (confusion, anxiety) are usually observed in patients with atherosclerotic parkinsonism. They should begin treatment with very low doses and slowly increase in dose as therapy continues.
Nervous system: headache, dizziness, irritability, delusions, hallucinations, fatigue, decreased ability to concentrate, psychosis.
Digestive system: nausea, vomiting. Allergic reactions: skin rash. Other reactions: dryness of the oral mucosa, paresis of accommodation, high intraocular pressure, constipation, urinary retention, tachycardia, sweating, decreased salivation, flushing, drug dependence.
What should I know about Artane (trihexyphenidyl) contraindications?
Artane (trihexyphenidyl) contraindications: hypersensitivity to any component of the drug, nonmalignant stenosis of the gastrointestinal tract, angle-closure glaucoma, urinary retention, prostatic hyperplasia, pulmonary edema, dementia, children's age (up to 12 years), pregnancy, lactation. Artane precautions: decompensated heart failure, kidney or liver disease, tachycardia, tachyarrhythmia, hypertension, psychosis, acute myocardial infarction.
Artane (trihexyphenidyl) overdose
Large doses of the drug may cause mydriasis, dry mouth, tachycardia, fever, disorders of the central nervous system (mental and motor excitation, coma, paralysis of the respiratory center). Treatment: there is no specific antidote. Treatment is symptomatic and supportive.
Artane (trihexyphenidyl) interaction with other drugs
Artane (trihexyphenidyl) should not be used with H1 histamine receptor blockers, phenothiazine derivatives, tricyclic antidepressants.
Antiparkinsonian effect of trihexyphenidyl is reduced under the influence of reserpine.
Levodopa increases the effect of trihexyphenidyl. When used together with levodopa, the dosage of both drugs should be reduced. In this case, 3-6 mg of trihexyphenidyl per day is enough (divided into two doses).
Monoamine oxidase inhibitors may increase the anticholinergic effect of trihexyphenidyl.
Artane may reduce the effect of sublingual nitrates (due to dry mouth).
Depressive effects of alcohol and drugs that affect the central nervous system may be enhanced when used with trihexyphenidyl.
Artane (trihexyphenidyl) special instructions
Artane (trihexyphenidyl) should be used with caution in hypertension, liver and kidney diseases.
During the period of treatment, patients should refrain from driving and performing potentially hazardous activities.
Patients older than 60 years should use Artane with extreme caution (high risk of sensitivity to the drug).
Stopping your medication abruptly may adversely affect your condition. Trihexyphenidyl dose should be reduced gradually.