Calan (verapamil) Coupons, Discounts & Cost
Calan (verapamil) is a drug with antiarrhythmic, antianginal and antihypertensive action. One way to save money on the Calan (verapamil) retail cost regardless of income and insurance status is to use Calan (verapamil) coupons or discount cards from RXCoupons. Use this Calan (verapamil) coupon at this online pharmacy and receive up to 75% off the sale price.
Calan (verapamil) pharmacologic effect
Calan (verapamil) is a drug with antiarrhythmic, antianginal and antihypertensive action. The drug is known to reduce myocardial oxygen demand. It helps reduce myocardial contractility and increase coronary blood flow. Verapamil significantly slows AV conduction, which is essential for the treatment of supraventricular arrhythmias.
Calan tablets are widely used to treat cardiac arrhythmias (including paroxysmal supraventricular tachycardia), atrial flutter, supraventricular arrhythmias, unstable angina, chronic stable angina, vasospastic angina (Prinzmetal angina), hypertension.
Calan (verapamil) contraindications
Calan (verapamil) absolute contraindications: chronic heart failure (class II-III), Stokes–Adams syndrome, sinoatrial block, sick sinus syndrome, cardiogenic shock (for tablets), severe bradycardia (for tablets), acute heart failure (for tablets), atrioventricular block (II and III degree, except patients with artificial pacemaker), hypotension (for injection), acute myocardial infarction (for injection), aortic stenosis (for injection), ventricular tachycardia (for injection), porphyria (for injection), concurrent therapy with intravenous beta-blockers, age up to 18 years, pregnancy and lactation, hypersensitivity to the drug.
Calan (verapamil) should be used with caution under the following conditions: atrioventricular block (I degree), bradycardia, severe functional disorders of the kidneys and liver, hypotension (for tablets), chronic heart failure (class I and II), concurrent therapy with beta-blockers (for injection), significant left ventricular dysfunction, elderly patients (for injection).
Calan (verapamil) dosage
Calan (verapamil) tablets should be taken with a small amount of water, during or after a meal. The dosage regimen and duration of therapy should be set individually (depending on the condition of the patient and the severity of the disease).
The initial adult dose in the treatment of hypertension and for the prevention of strokes and arrhythmia is 40-80 mg, the multiplicity of reception - 3-4 times a day. If necessary, a single dose may be increased to 120-160 mg (max - 480 mg per day).
Patients with functional disorders of the liver should start the therapy with the lowest dose (maximum - 120 mg per day).
Verapamil should not be used for 7 days after myocardial infarction.
Side effects of Calan (verapamil)
Central nervous system: headache, dizziness, in rare cases - lethargy, fatigue. Digestive system: vomiting, nausea, constipation. Cardiovascular system: facial flushing, AV-block, bradycardia, hypotension, symptoms of heart failure (when using high doses of the drug, especially in predisposed patients). Musculoskeletal system: muscle weakness, myalgia, arthralgia. Immune system: hypersensitivity, angioedema. Allergic reactions: itching, skin rash. Other reactions: peripheral edema. Overdose symptoms: high doses can cause hypotension, sinus bradycardia, AV block.
Calan (verapamil) cautions
It is necessary to control the function of the respiratory and cardiovascular systems during treatment. Do not discontinue the therapy abruptly.
Verapamil should be used with caution in drivers and people whose profession is associated with periods of high concentration.
Calan (verapamil) interactions
Calan (verapamil) should not be used with certain drugs (high risk of side effects).
Antiarrhythmic agents, beta-blockers and inhaled anesthetics may increase cardiotoxic effects (atrioventricular block, heart failure, sudden fall in blood pressure).
Antihypertensives and diuretics may increase the hypotensive effect of verapamil.
Verapamil may increase the levels of digoxin, theophylline, quinidine, prazosin, cyclosporin in plasma.
Cimetidine and ranitidine may increase the concentration of verapamil in plasma.
Rifampicin and phenobarbital decrease verapamil concentrations.
Aspirin may increase the risk of bleeding.
Carbamazepine and lithium may cause neurotoxic effects.