Cordarone (amiodarone) Coupons and Discounts & Cost
Amiodarone Hydrochloride is undoubtedly the most effective anti-arrhythmic drug. One way to save money on the Cordarone (amiodarone) retail cost regardless of income and insurance status is to use Cordarone (amiodarone) coupons or discount cards from RXCoupons. Use our Cordarone (amiodarone) coupons at your online pharmacy and receive up to 75% off the sale price each time you refill your prescription.
Cordarone (amiodarone) effects
Amiodarone Hydrochloride is undoubtedly the most effective anti-arrhythmic drug. It has also antianginal, moderate hypotensive and antioxidant action.
Cordarone (amiodarone) indications
Amiodarone Hydrochloride is used to treat life-threatening ventricular arrhythmias (including ventricular tachycardia, ventricular fibrillation), supraventricular arrhythmias (including organic diseases of the heart), atrial fibrillation and atrial flutter.
Amiodarone CHL contraindications
Do not use this substance in case of sinus bradycardia, 2nd and 3rd degree AV block, severe hypotension, dysfunction of the thyroid gland (hypothyroidism and hyperthyroidism), pregnancy and lactation;
Amiodarone CHL should not be used with drugs that prolong the QT interval or may cause paroxysmal tachycardia. The agent should not be used with antiarrhythmics and some other drugs, such as bepridil, some antipsychotics, benzamides, tricyclic antidepressants, macrolide antibiotics.
Amiodarone CHL is contraindicated in case of hypokalemia, hypomagnesemia, interstitial lung disease. Do not use this substance if you are under 18.
Precautions: hepatic failure, asthma, elderly patients (high risk of severe bradycardia), chronic heart failure, first degree AV block.
Amiodarone CHL dosage
The tablets are taken before meals, with plenty of fluids. The dosage should be determined by your doctor.
Amiodarone CHL maintenance therapy includes the lowest effective dose depending on the individual response of the patient.
The average therapeutic single dose is 200 mg.
The average therapeutic daily dose is 400 mg.
Amiodarone CHL overdose
Amiodarone CHL therapy should be discontinued in case of toxicity.
Symptoms of overdose: low blood pressure, sinus bradycardia, arrhythmia, liver dysfunction, cardiac arrest.
Gastric lavage and activated charcoal are used in the emergency treatment of Amiodarone CHL overdose.
Amiodarone CHL interactions
Amiodarone CHL is contraindicated in combination with class I antiarrhythmic agents, antipsychotic drugs, tricyclic antidepressants, antimalarial drugs.
Amiodarone CHL is not recommended in combinations with some beta-blockers, drugs that cause hypokalemia (diuretics, systemic corticosteroids), indirect anticoagulants, cardiac glycosides.
Rifampicin and St. John's wort preparations may reduce the level of concentration of Amiodarone.
Amiodarone CHL is contraindicated during pregnancy and lactation, since Amiodarone may cause hypothyroidism (due to increased concentrations of iodine). The drug is contraindicated during lactation (Amiodarone is excreted in breast milk in significant amounts).
Amiodarone CHL side effects
All side effects of Amiodarone CHL are almost always reversible. They disappear after canceling or reducing the dose of Amiodarone.
Cardiovascular system: moderate bradycardia, arrhythmia, sinus arrest, chronic heart failure symptoms.
Digestive system: nausea, vomiting, decreased appetite, acute toxic hepatitis, chronic liver failure.
Respiratory system: pneumonitis, pleural effusion, pulmonary fibrosis, bronchospasm in patients with acute respiratory failure.
Endocrine system: long-term Amiodarone use may cause hypothyroidism or hyperthyroidism.
Dermatological reactions: photosensitivity, erythema, rash, exfoliative dermatitis, vasculitis, alopecia.
Nervous system: tremor, other extrapyramidal symptoms, peripheral neuropathy, headache.
Other reactions: thrombocytopenia, aplastic anemia.
Cordarone (amiodarone) special instructions
Patients should regularly monitor the activity of liver enzymes during treatment with Amiodarone. Patients should avoid sun exposure or use effective protective measures.
Amiodarone may be used in pregnancy and lactation only if other antiarrhythmic therapy is ineffective (Amiodarone may cause thyroid disorders during pregnancy). Before starting treatment and for several months after treatment, it is necessary to regularly monitor thyroid function.
Caution should be exercised when used in general anesthesia (high risk for developing bradycardia).
During treatment with Cordarone (amiodarone), patients should not drive. They should avoid potentially dangerous activities that require concentration and other psychomotor abilities.