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Effient (prasugrel) Coupons, Discounts & Cost

Effient (prasugrel) is an antithrombotic drug. One way to save money on the Effient (prasugrel) retail cost regardless of income and insurance status is to use Effient (prasugrel) coupons or discount cards from RXCoupons. Use our Effient (prasugrel) coupons at your online pharmacy and receive up to 75% off the sale price each time you refill your prescription.

What do patients need to know about Effient (prasugrel)?

Effient (prasugrel) is an antithrombotic drug. It is used to decrease the frequency of death and prevent cardiovascular events such as myocardial infarction or stroke.

Effient is used in combination with acetylsalicylic acid in patients undergoing percutaneous coronary intervention. It is effective for the prevention of atherothrombotic events (myocardial infarction, stroke, cardiovascular death) in patients with acute coronary syndrome (unstable angina, non-ST elevation myocardial infarction, ST elevation myocardial infarction).

How should patients use Effient (prasugrel)?

The initial single loading dose is 60 mg, followed by maintenance dose of 10 mg 1 time per day. Patients taking prasugrel should also take aspirin at a dose of 75 mg to 325 mg daily.

Patients weighing <60 kg should take the maintenance dose of 5 mg.

In what cases patients should NOT take Effient (prasugrel)?

Do not take Effient (prasugrel) without consulting your physician in case if you have acute abnormal bleeding, transient ischemic attack, severe hepatic impairment, hypersensitivity to prasugrel.

It is possible to take prasugrel during pregnancy only when the expected benefits of therapy outweigh the potential risks.

What are the possible side effects of Effient (prasugrel)?

Blood: often - bleeding. Hematopoiesis: severe thrombocytopenia, anemia, leucopenia. Digestive system: abnormal liver function tests, nausea, vomiting, diarrhea. Cardiovascular system: hypertension, hypotension, atrial fibrillation, bradycardia. Metabolism: hypercholesterolemia, hyperlipidemia. Nervous system: headache, dizziness. Respiratory system: dyspnea, cough. Other systems: allergic reactions (including angioedema), back pain, weakness, non-cardiac chest pain, rash, fever, peripheral edema, thrombocytopenic purpura, hypersensitivity reactions (including anaphylactic reactions).

Effient (prasugrel) special instructions

Prasugrel should be used with caution in patients aged 75 years and older (only after careful individual evaluation of future risks). This category of patients should use prasugrel at a dose of 5 mg 1 time per day (doses of 10 mg per day are not recommended). It should be borne in mind that patients aged 75 years and older are at higher risk of bleeding (including fatal bleeding) compared to patients younger than 75 years.

Prasugrel should be used with caution in patients weighing less than 60 kg.

Caution should be used in patients with bleeding associated with recent trauma, surgery, gastrointestinal bleeding, severe renal impairment.

Prasugrel should be used with caution in combination therapy with drugs that can increase the risk of bleeding (including oral anticoagulants, NSAIDs, and fibrinolytic agents).

Patients should tell their doctor about all cases of bleeding during treatment with prasugrel.

Patients should tell the doctor and dentist about prasugrel therapy before any surgical procedure. Prasugrel should be discontinued at least 7 days prior to surgery.

Prasugrel may increase the risk of thrombosis and myocardial infarction in patients with acute coronary syndrome.

Patients with impaired renal function (including patients with end-stage renal disease) may not change the dose of the drug. Patients with mild or moderate hepatic impairment may not change the dose of the drug as well. Prasugrel should not be used in patients with severe liver disease (due to the potential risk of bleeding).

Prasugrel may be used in conjunction with acetylsalicylic acid (75-325 mg per day), statins, digoxin, and medications that raise intragastric pH (including proton pump inhibitors and H2 blockers). Warfarin and NSAIDs may increase the risk of bleeding.

Efficacy and safety of Effient have not been established in pediatric patients.

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