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Glucotrol

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Glucotrol (glipizide) Coupons, Discounts & Cost

Glucotrol (glipizide) belongs to the group of 2nd generation sulfonylurea drugs used for the treatment of insulin-independent diabetes. One way to save money on the Glucotrol (glipizide) retail cost regardless of income and insurance status is to use Glucotrol coupons or discount cards from RXCoupons. Use our Glipizide coupons at your online pharmacy and receive up to 75% off the sale price each time you refill your prescription.

Why do you need to take Glucotrol (glipizide)?

Glucotrol (glipizide) belongs to the group of 2nd generation sulfonylurea drugs used for the treatment of insulin-independent diabetes. Glipizide stimulates insulin secretion, inhibits platelet aggregation and increases sensitivity of liver cells to insulin. The drug has fibrinolytic, lipid-lowering, and mild diuretic action.

After ingestion, glipizide is completely absorbed in the gastrointestinal tract. The half-life is 2-4 hours.

Glucotrol (glipizide) dosage and administration

The initial dose is usually 2.5-5 mg per day. The maximum dose is 30 mg per day. Small doses are taken once daily, while doses above 15 mg - 2-3 times a day.

Side effects of Glucotrol (glipizide)

Possible side effects may include headache, dyspepsia (indigestion), allergic reactions (itching, dermatitis, skin inflammation), leukopenia, thrombocytopenia, abnormality in liver function tests. Reduce the dose of Glucotrol in case of hypoglycemia.

Central nervous system: headache, dizziness, depression, confusion, paresthesia, hyperesthesia. Hematopoietic system: rarely - thrombocytopenia, erythropenia, granulocytopenia, hemolytic anemia. Respiratory system: pharyngitis, rhinitis, dyspnea. Circulatory system: peripheral edema. Digestive system: dyspepsia, nausea, vomiting, constipation. Musculoskeletal system: arthralgia, myalgia, convulsions. Dermatological reactions: rash, photosensitivity. Urinary system: proteinuria, dysuria. Reproductive system: decreased libido. Other disorders: conjunctivitis, allergic reactions.

When Glucotrol (glipizide) is contraindicated?

Avoid this drug in case of temporary loss of consciousness and coma (complete loss of consciousness), ketoacidosis. Do not use Glucotrol in children, in women during pregnancy and lactation, in case of Insulin-dependent diabetes, acute infectious disease of the liver and kidney, leucopenia, granulocytopenia, allergic reactions to sulfonamides.

This drug should be taken with caution in case of disorders of carbohydrate metabolism, adrenocortical insufficiency, thyroid dysfunction.

Glucotrol (glipizide) interaction

Ketoconazole, cyclosporine, erythromycin may increase the concentration of the drug in blood plasma.

Avoid using Glucotrol with thiazide diuretics, calcium channel blockers, lithium drugs, corticosteroids, isoniazid, sympathomimetics, niacin, phenytoin, phenothiazines, thyroid hormones.

ACE inhibitors (captopril, enalapril), antifungal drugs (miconazole, fluconazole), salicylates, anabolic steroids, tetracycline, bromocriptine, pyridoxine, insulin and allopurinol may enhance the effect of Glucotrol.

Indirect anticoagulants, MAO inhibitors, NSAIDs, chloramphenicol, cyclophosphamide and probenecid may increase the hypoglycemic effect of the drug. However, the hypoglycemic effect may be lower with concomitant administration of epinephrine, corticosteroids, oral contraceptives, barbiturates, antiepileptic drugs (phenytoin), thiazide diuretics, furosemide, triamterene, baclofen, morphine, salbutamol, glucagon, rifampicin, nicotinic acid.

If the drug is used with furosemide, it is necessary to reduce the dose of glipizide.

Alcohol consumption during treatment (especially on an empty stomach) may increase the risk of hypoglycemia.

Special instructions for Glucotrol (glipizide)

Avoid using Glucotrol (glipizide) during pregnancy and lactation.

Glipizide is used with caution in patients having allergic reactions to sulfonylurea derivatives.

Patients previously treated with other oral hypoglycemic drugs and patients on insulin therapy should be carefully monitored.

Patients should monitor their blood-glucose levels regularly.

The doses of the drug may be reduced in case of trauma, surgery, infectious diseases.

Glipizide may cause hypoglycemia. The risk of hypoglycemia is higher in debilitated patients, elderly patients, in case of eating disorders or alcohol abuse, as well as in patients with impaired liver and hepatic function.

It is not recommended to drive during the initial period of treatment with Glucotrol.

Glucotrol (glipizide) storage conditions

The drug should be stored at a temperature not exceeding 30° C.

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