Hyzaar (losartan) Coupons, Discounts & Cost
Hyzaar (losartan) is an antihypertensive drug containing losartan and hydrochlorothiazide. One way to save money on the Hyzaar (losartan) retail cost regardless of income and insurance status is to use Hyzaar coupons or discount cards from RXCoupons. Use our Losartan coupons at your online pharmacy and receive up to 75% off the sale price each time you refill your prescription.
What should I know about Hyzaar (losartan)?
Hyzaar (losartan) is an antihypertensive drug containing losartan and hydrochlorothiazide. It is used to treat hypertension (in patients who need to take combination therapy). The drug is also used to reduce the risk of cardiovascular events and mortality in left ventricular hypertrophy and hypertension.
Hyzaar (losartan) main contraindications
The drug is not used in people younger than 18 years. It is also contraindicated in severe hepatic impairment, severe renal impairment, anuria, glucose-galactose malabsorption, lactose intolerance, lactase deficiency, hypersensitivity to sulfonamides. Hyzaar is not prescribed during pregnancy and breastfeeding. Caution is recommended in patients with renal insufficiency, bilateral renal artery stenosis, fluid and electrolyte disorders caused by vomiting or diarrhea (hyponatremia, hypomagnesemia, hypokalemia), gout, hypercalcemia, hyperuricemia, diabetes, asthma, hypovolemia (including in patients taking high doses of diuretics), connective tissue diseases (including systemic lupus erythematosus).
Do not take Hyzaar with non-steroidal anti-inflammatory drugs.
Hyzaar (losartan) Dosage and administration
Take the tablets regardless of meals. Recommended dosage: 1 tablet 1 time per day. The dose can be increased to 2 tablets one time per day after three weeks of treatment. The maximum daily dose is 2 tablets.
Hyzaar (losartan) side effects
The most commonly observed adverse reactions include: weakness, dizziness, fatigue. Digestive system: rarely - diarrhea, hepatitis. Allergic reactions: anaphylactic reactions, angioedema, rarely - vasculitis. Dermatological reactions: rash, increased sensitivity to light. Respiratory system: rarely - cough. Other reactions: rarely - hyperkalemia.
Hyzaar (losartan) overdose
Symptoms: losartan - low blood pressure, tachycardia, bradycardia. Hydrochlorothiazide - hypokalemia, hyposalemia, hyponatremia. Treatment of overdose: Symptomatic and supportive therapy.
Hyzaar (losartan) Specific guidance
Hyzaar is used in combination with other antihypertensive agents. Losartan may cause changes in renal function, renal failure. The drug may also cause symptomatic hypotension.
Patients should regularly monitor water and electrolyte balance to identify the clinical signs of hyponatremia, dehydration, hypokalemia, hypomagnesemia.
Elderly patients may not change the starting dose of the drug.
Some patients may need to change the doses of insulin and other hypoglycemic agents. Thiazides may cause a slight increase in the concentration of calcium and reduce calcium excretion in the urine. Thiazide diuretics may increase the level of triglycerides and cholesterol in the blood.
There are no clear data about the symptoms of overdose. High doses of Hyzaar may lead to hypotension, slow heart rate.
Do not use Hyzaar in pregnant women. The drug can cause fetal death. Cancel this preparation or choose analogues of the drug if you are pregnant. The drug has teratogenic effects and can provoke death of the newborn. The risk of teratogenic effects is higher when taking the drug during 2-3 trimesters of pregnancy. Also, Hyzaar can provoke fetal jaundice in neonatal patients and thrombocytopenia in women during pregnancy.
Hyzaar (losartan) interaction
Potassium-sparing diuretics including spironolactone, triamterene, amiloride, potassium salts or potassium-containing additives can increase the concentration of potassium. The therapeutic effect of the drug may be reduced if combined with non-steroidal anti-inflammatory agents.
Concomitant therapy with ethanol, barbiturates, opioid analgesics may increase the risk of orthostatic hypotension. Cholestyramine may significantly reduce the absorption of hydrochlorothiazide.
The drug enhances the effect of nondepolarizing muscle relaxants.
Hyzaar (losartan) Conditions of storage
Store out of the reach of children, at a temperature of 15-30° C.