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Lioresal (baclofen) Coupons, Discounts & Cost

Lioresal (baclofen) is a drug from the group of muscle relaxants. One way to save money on the Lioresal (baclofen) retail cost regardless of income and insurance status is to use Lioresal (baclofen) coupons or discount cards from RXCoupons. Use our Lioresal (baclofen) coupons at your online pharmacy and receive up to 75% off the sale price each time you refill your prescription.

What is Lioresal (baclofen)?

Lioresal (baclofen) is a drug from the group of muscle relaxants. The active compound is baclofen - a neurotransmitter involved in the functions of the central nervous system.

Baclofen significantly reduces the intensity of muscle spasms and reduces the frequency of seizures. As a result, the therapy leads to increased motor activity and normal function of the bladder.

Lioresal (baclofen) may cause sedation. The best effect is observed 30 or 60 minutes after infusion.

What are Lioresal (baclofen) indications for use?

Lioresal (baclofen) is indicated in severe spasticity in multiple sclerosis, in case of stroke, traumatic brain injury, meningitis, spinal diseases (of infectious, degenerative, traumatic and tumoral origin), cerebral palsy, alcoholism (affective disorders).

What are Lioresal (baclofen) contraindications?

Lioresal (baclofen) should be avoided in children less than four years old. This drug is not prescribed in case of hypersensitivity to baclofen. Furthermore, baclofen should not be administered subcutaneously, intravenously, intramuscularly, or into the epidural space. The agent in the form of solution is administered only into the subarachnoid space.

This muscle relaxant is prescribed with caution in the elderly, in patients with impaired cerebrospinal fluid circulation, in psychiatric disorders, Parkinson's disease, schizophrenia, diabetes, epilepsy, dysreflexia, respiratory failure, as well as in some other disorders.

What is the recommended dosage for Lioresal (baclofen)?

Lioresal (solution) is administered by the intrathecal route. The drug helps decrease muscle tone and severity of seizures. The amount of drug varies from 25 to 50 micrograms.

Usual maintenance dose ranges from 12 to 2000 mcg a day. The majority of patients use 300-800 mcg during the day. Discontinuation should be carried out gradually by reducing the dose of the drug.

Lioresal tablets should be taken during a meal. The initial dose is 5 mg 3 times a day. The dose may be increased every 3 days by 5 mg, usually no more than 20-25 mg 3 times a day. The maximum possible dose is 100 mg a day (for a short time).

Children under 10 years old should use 0.75-2 mg/kg; children over 10 years old - 2.5 mg/kg. The initial dose for children of 1-2 years is 1.5-2 mg/kg 4 times a day. Discuss with your doctor if you want to gradually discontinue Lioresal therapy (within 1-2 weeks).

What about Lioresal (baclofen) overdose?

The following overdose symptoms may occur: severe muscular hypotonia, seizures, drowsiness, dizziness, blurred consciousness, hypothermia, nausea, excessive salivation, vomiting.

Treatment: drinking more liquids, diuretics.

What are some of Lioresal (baclofen) side effects?

Lioresal therapy may lead to the following side effects: somnolence, hypotonia, dizziness, low pressure, headache, nausea, sedation, convulsions, paresthesia, disturbances of accommodation, fatigue, nystagmus, confusion, as well as euphoria, hallucinations.

In addition, some patients may experience hypotension, dyspnea, bradycardia, venous thrombosis, pneumonia, skin redness, nausea, constipation, rash, dry mouth, increased sweating, diarrhea, decreased appetite, dehydration, urinary retention, ileus, muscular hypotonia, hyperglycemia.

Some side effects are usually transient.

Lioresal (baclofen) specific guidance

There is a risk of complications during Lioresal treatment, in particular, respiratory depression, CNS depression, collapse.

Patients with liver disease and diabetes should periodically monitor liver enzyme activity, alkaline phosphatase and glucose levels.

During treatment, patients should refrain from potentially hazardous activities related to increased attention and rapid motor responses.

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