Minipress (prazosin) Coupons, Discounts & Cost
Minipress is a drug with antihypertensive and vasodilating effect. One way to save money on the Minipress retail cost regardless of income and insurance status is to use Minipress coupons or discount cards from RXCoupons. Use this Prazosin coupon at this online pharmacy and receive up to 75% off the sale price.
Minipress - what it is?
Minipress is a drug with antihypertensive and vasodilating effect. Prazosin is a blood pressure lowering agent used for the treatment of hypertension (persistent rise in blood pressure) and congestive heart failure.
Main effects of Minipress
The drug lowers blood pressure by decreasing total peripheral vascular resistance. Prazosin usually does not cause changes in heart rate (even in patients with heart failure). It helps reduce the blood concentration of atherogenic lipids.
The drug does not cause suppressed plasma renin activity. However, long term administration of prazosin can cause sodium and water retention.
The maximum concentration is achieved within 1-3 hours after ingestion.
What are the precautions when taking Minipress?
Absolute contraindications: heart failure with reduced left ventricular ejection fraction, constrictive pericarditis, hypotension, cardiac tamponade, pregnancy and lactation, hypersensitivity to the drug. Minipress is not used in children under the age of 12 years.
What is the best way to take this drug?
Hypertension: the initial dose for the beginning of the treatment is 0.5 mg (at bedtime). Gradually increase the dose to 1 mg 3-4 times a day. The optimal daily dose for the patient may vary from 3 to 20 mg. The usual dose is 6-15 mg. The total daily dose is divided into 3-4 doses.
Congestive heart failure: take 3-20 mg per day in 3-4 divided doses. The maximum tolerable daily intake for adults is 20 mg.
Prazosin as a single agent can lead to reduced reaction to the drug (in the beginning of treatment or after a few months). In this case, patients should increase the dose of prazosin or take diuretics. They should also use other antihypertensive drugs or diuretics in case of insufficient hypotensive effect.
The hypotensive effect of prazosin depends on the patient’s age. Therefore, the dose should be chosen carefully for elderly persons.
Main effects
What are some side effects of Minipress?
The most significant side effect of prazosin is the so-called “first dose effect”. This phenomenon is observed in the first days of treatment and is characterized by dizziness, headache, and loss of consciousness (in rare cases).
Central and peripheral nervous system: headaches, weakness, vertigo, sleep disorders, mood disorders, hallucinations, anxiety, depression, fatigue, paresthesia.
Cardiovascular system: chest pain, shortness of breath, tachycardia, palpitation, hypotension (especially postural hypotension); long-term use - leg swelling; rarely - orthostatic hypotension (usually after the first dose).
Urinary system: frequent urination.
Digestive system: diarrhea or constipation, nausea, vomiting, dry mouth.
Allergic reactions: skin rash, itching.
Other reactions: blurred vision, redness of the conjunctiva and cornea, tinnitus, pyrexia, nasal congestion, arthralgia, nasal bleeding, alopecia, decreased potency, priapism.
During treatment, you must constantly monitor your heart rate and blood pressure. The risk of hypotension is higher in patients taking beta-blockers, diuretics and sympatholytic drugs.
Special instructions for Minipress
Prazosin should not be used with nifedipine, sympatholytic drugs, diuretics, beta-blockers. Beta-blockers, ACE inhibitors, and calcium channel blockers increase the risk of severe arterial hypotension (especially after the first dose of prazosin).
Indometacin may reduce the effect of prazosin. Prazosin promotes significant increase of digoxin levels. This drug may also change the antihypertensive effects of clonidine. There is a risk of severe arterial hypertension in patients receiving propranolol (after the first dose of prazosin).
Minipress storage conditions
Store at temperatures up to 25° C, in a dark, dry place, out of reach of children.