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Pentasa (mesalamine) Coupons, Discounts & Cost

Pentasa belongs to the group of anti-inflammatory drugs that are used to treat certain inflammatory bowel diseases. One way to save money on the Pentasa retail cost regardless of income and insurance status is to use Pentasa coupons or discount cards from RXCoupons. Use this Mesalamine coupon at this online pharmacy and receive up to 75% off the sale price.

Learn about Pentasa

Pentasa belongs to the group of anti-inflammatory drugs that are used to treat certain inflammatory bowel diseases. The active substance is mesalamine.

Pentasa is used for the treatment of Crohn's disease and ulcerative colitis. The drug has anti-inflammatory effect. Moreover, it has antibacterial effect on certain pathogens. Mesalamine significantly reduces the risk of recurrence of Crohn's disease. The drug is excreted mainly by the kidneys and intestines. Approximately 1\3-1\2 of the drug is absorbed in the small intestine.

Pentasa indications and recommendations

This drug is recommended for the following states: Crohn's disease, nonspecific ulcerative colitis. The tablets should be swallowed whole, without chewing.

Pentasa therapy for ulcerative colitis is prescribed by the attending physician individually for each patient. It is recommended to take up to 4 g of the drug per day by dividing this dose into several doses.

As for children, it is recommended to use 20-30 mg per kg of body weight per day.

Maintenance therapy: take the drug at a dosage of 2 g per day (divide this dose into several doses).

The recommended maximum dose of the drug is 4 g per day.

Learn about Pentasa contraindications

This drug is contraindicated in patients who have individual intolerance of the main or auxiliary component of Pentasa. Also, this drug is not used for the treatment of patients with severely impaired renal function. Do not use this drug in patients with blood diseases, gastric ulcer and duodenal ulcer, hemorrhagic diathesis, severe renal or hepatic insufficiency.

Pentasa is absolutely contraindicated in women during the last 2-4 weeks of pregnancy, as well as in children under the age of 2 years. In addition, use caution during the I ‚Äč‚Äčtrimester of pregnancy. Women during lactation should avoid this drug.

Learn about Pentasa side effects

Numerous positive comments confirm that the drug is well tolerated by the majority of patients. However, some reviews have reported various side effects that occur while taking Pentasa. In rare cases, patients may have nausea, diarrhea, vomiting, abdominal pain, and headache, allergic reactions (urticaria, rash and pruritus). There are individual effects such as myalgia and arthralgia, shortness of breath, hair loss, pancreatitis, impaired liver function.

Various side effects of the cardiovascular system: oliguria, hematuria, anuria.

CNS side effects: tinnitus, depression, dizziness, polyneuropathy.

Hematopoietic system: eosinophilia, anemia, agranulocytosis.

Excretory system: proteinuria, hematuria, anuria.

Allergic reactions: itching and burning of the skin.

You should immediately contact your doctor in case of dangerous effects.

Learn about Pentasa interactions

Pentasa increases the toxicity of azathioprine, mercaptopurine, and methotrexate.

Pentasa reduces the effectiveness of warfarin (in combination therapy).

The drug potentiates the hypoglycemic effect of sulfonylureas.

Pentasa increases the carcinogenicity of glucocorticoids.

The drug inhibits the absorption of vitamin B 12.

Pentasa enhances the effect of anticoagulants.

Learn about Pentasa overdose

Symptoms of overdose include nausea, vomiting, gastralgia, weakness, drowsiness. Treatment is symptomatic: gastric lavage, laxatives, monitoring of renal function.

Additional information

Pentasa can be administered in the majority of patients who have allergic reaction or risk of developing allergies to salicylates.

Caution should be used in patients with impaired hepatic function. Do not use the drug in patients with renal insufficiency. Violations of normal renal function during treatment may be caused by nephrotoxic effect of Pentasa.

Patients should remove this drug in case of unwanted symptoms such as cardiovascular and respiratory disorders.

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