Phenergan (promethazine) Coupons, Discounts & Cost
Phenergan (promethazine) is a potent antihistamine agent used to reduce allergic reactions. One way to save money on the Pepcid retail cost regardless of income and insurance status is to use Pepcid coupons or discount cards from RXCoupons. Use this Famotidine coupon at this online pharmacy and receive up to 75% off the sale price.
What is Phenergan
Phenergan (promethazine) is a potent antihistamine agent used to reduce allergic reactions. Promethazine is also used in the treatment of insomnia.
This drug with antihistaminic activity has antiemetic, sedative, hypnotic, anti-psychotic, hypothermic effects. It helps prevent hiccup, urticaria and pruritus.
The clinical effect occurs within 15-60 minutes and lasts for 6-12 hours. The drug is well absorbed from the GT. It is excreted mainly via the kidneys and bile (to a lesser extent).
Phenergan medical indications for use
The drug is used to treat eczema, exudative diathesis, urticaria, rash, prurigo and other allergic reactions to drugs and chemicals, as well as itching, allergic conjunctivitis, allergic rhinitis, hay fever, insect bites serum sickness, angioneurotic edema, asthmatic bronchitis, anaphylactic and anaphylactoid reactions (in the complex therapy), Meniere's syndrome, dizziness, nausea and vomiting, motion sickness syndrome.
Promethazine is effective in the treatment of anxiety, psychosis, insomnia, extrapyramidal disorder (while taking neuroleptics), migraine, chorea, hyperthermia. It is used as a sedative in premedication and postoperative period.
Phenergan contraindications
Promethazine should be avoided in the following cases: hypersensitivity (including to other phenothiazines), alcohol intoxication, liver and/or kidney failure, pregnancy, breastfeeding, combination therapy with MAO inhibitors, children under 6 years of age.
Use with caution in the following cases: jaundice, prostatic hypertrophy, predisposition to urinary retention, open- and closed-angle glaucoma, peptic ulcer, lower respiratory tract disease, inhibition of bone marrow function, diseases of the cardiovascular system (severe angina pectoris, hypertension, decompensated chronic heart failure, atrial tachyarrhythmia), epilepsy, sleep apnea syndrome, Reye syndrome.
Promethazine is contraindicated during pregnancy. Patients should also stop breastfeeding.
Phenergan instructions for use
Take the tablets after a meal. Adults: 12.5-25 mg 3-4 times during the day and 25-50 mg per night.
Nausea and vomiting - 25 mg at the beginning of treatment, and 12.5-25 mg every 4-6 hours. Children aged 2-6 years - 12.5 mg, 6-14 years - 25 mg 3-4 times per day.
Before surgery - 25-50 mg together with other drugs.
Prevention of motion sickness syndrome: 25-50 mg for adults (once for 1 h before the trip), 10-20 mg for children.
Possible side effects
Nervous system and sensory organs: sedation, dizziness, drowsiness, anxiety, agitation, nightmares, increased sleep apnea; rarely - disorientation, confusion, extrapyramidal disorder, noise or ringing in the ears.
Cardiovascular system and hemostasis: orthostatic hypotension, hypertension, tachycardia or bradycardia; rarely - leukopenia, thrombocytopenia, agranulocytosis.
Digestive tract: anesthetic and dry mouth, nausea, vomiting, cholestasis, constipation.
Respiratory system: dry nose and throat.
Urogenital system: rarely - difficulty or painful urination.
Allergic reactions: rash, dermatitis, asthma.
Other reactions: increased sweating, photosensitivity.
Different signs of overdose
Symptoms: flushing of the face, shortness of breath, dry mucous membranes, dilated pupils, restlessness, motor hyperactivity, agitation, delirium (in children), extrapyramidal disorder, tremor, hypotension, respiratory depression, loss of consciousness.
Treatment: vomiting, activated carbon, saline laxatives, symptomatic therapy. Dialysis is ineffective.
Phenergan special instructions
Beta blockers may lead to severe hypotension, arrhythmia, irreversible retinopathy, tardive dyskinesia.
Analgesics, sedatives, tranquilizers, antipsychotics, local anesthetics, antihypertensives should be used with caution together with Phenergan.
Barbiturates may reduce promethazine activity.
Bromocriptine may increase the concentration of prolactin.
MAO inhibitors, phenothiazine derivatives increase the risk of hypotension and extrapyramidal disorders (co-administration is not recommended).
Quinidine may increase the risk of cardiodepressive action.
Epinephrine may cause serious hypotension.
Avoid alcohol during treatment.
Use caution in children with acute or chronic respiratory diseases (promethazine may suppress the cough reflex).
Promethazine can be used in combination with opioid analgesics and tranquilizers only under strict medical supervision.
Caution should be used in people with impaired liver function and cardiovascular diseases.