Rifadin (rifampin) Coupons, Discounts & Cost
Rifadin is an antimicrobial agent and a semisynthetic antibiotic One way to save money on the Rifadin retail cost regardless of income and insurance status is to use Rifadin coupons or discount cards from RXCoupons. Use this Rifampin coupon at this online pharmacy and receive up to 75% off the sale price.
What is Rifadin?
Rifadin is an antimicrobial agent and a semisynthetic antibiotic used in all infectious processes, which are caused by microorganisms sensitive to rifampin: bronchitis, pneumonia, bronchopneumonia, lung abscesses, furunculosis, carbunculosis, infectious wounds, cholecystitis, cholangitis, cystitis, cystopyelitis, pyelonephritis, gonorrhea, otitis, tuberculosis of the lungs, urogenital tuberculosis. In addition, Rifadin is used in case of close contact with patients with meningococcal meningitis (for the prevention of the disease).
What about Rifadin main contraindications?
Rifadin main contraindications include: infectious hepatitis, jaundice, breastfeeding, pulmonary heart disease (II-III degree), chronic renal failure, hypersensitivity.
It is possible to use Rifadin during pregnancy only in critical situations. Use with caution in children from 2 to 12 months, as well as in patients with alcohol dependence and liver disease.
How to use this drug
Dosing recommendations for injections: - Tuberculosis (in combination with other antituberculous agents): adults with body weight up to 50 kg - 450 mg per day, adults with body weight of 50 kg and above - 600 mg per day; children - 10-20 mg per 1 kg per day. Duration of treatment depends on individual tolerability (1 month or more). The maximum daily dose is 600 mg. - Borderline leprosy: adults - 600 mg once a month in combination with clofazimine and dapsone. Duration of treatment: 24 months. - Borderline tuberculoid leprosy: 600 mg once a month in combination with dapsone, duration of treatment - 6 months. - Infectious pathologies caused by microorganisms sensitive to rifampin (with other antimicrobial agents): adults - 600-1200 mg per day, children - 10-20 mg per 1 kg of weight per day. Duration of treatment: 7-14 days (depending on the clinical effect). - Brucellosis: adults - 900 mg per day in combination with doxycycline. Duration of treatment: 1.5 months.
Dosing recommendations for capsules:
Rifadin is taken on an empty stomach or after meals.
The daily dose of Rifadin for adults is 600 mg per day, with severe forms of the disease - 900 mg per day.
The daily dose of Rifadin for children with pulmonary tuberculosis - 600 mg in one dose.
What about Rifadin main side effects?
CNS: headache, disorientation, ataxia, decreased visual acuity.
Digestive system: nausea, vomiting, decreased appetite or anorexia, diarrhea, hyperbilirubinemia, pseudomembranous colitis, hepatitis, erosive gastritis.
Urinary system: interstitial nephritis.
Allergic reactions: urticaria, fever, angioedema, bronchospasm, eosinophilia, arthralgia.
Other side effects: myasthenia gravis (muscle weakness), dysmenorrhea, leukopenia, thrombocytopenic purpura, acute renal failure, hemolytic anemia, flu-like syndrome (accompanied by headache, fever, chills, dizziness, myalgia).
In addition, Rifadin therapy can cause nephronecrosis, exacerbation of gout, hyperuricemia, phlebitis.
Rifadin specific guidance
This drug should be used with other antimicrobial agents (as part of combination therapy).
The drug should be canceled if flu-like syndrome is complicated by shortness of breath, hemolytic anemia, thrombocytopenia, bronchospasm, kidney failure, shock.
Rifadin is used during pregnancy only in special cases (especially in the first trimester).
Patients should systematically monitor liver function in case of long-term therapy.
Rifadin should be used with caution together with oral hypoglycemic agents, indirect anticoagulants, hormonal contraceptives, antiarrhythmic agents (quinidine, disopyramide, tocainide, mexiletine), cardiac glycosides, glucocorticosteroids, phenytoin, dapsone, benzodiazepines, theophylline, cyclosporine, ketoconazole, itraconazole, cimetidine, enalapril.
Combination therapy with isoniazid and pyrazinamide may cause severe liver dysfunction in patients with liver disease.
Rifadin bioavailability of rifampicin will be lower when used with antacids, opiates, anticholinergics, and ketoconazole.