hello. I dug up some information for you about Toradol and I hope that it is going to be helpful, I mostly searched for the side effects. I should start by saying that the generic name of this drug is ketorolac, ketorolac tromethamine. from as much as I could find about it, it does sound that the injection usually is having lesser reported side effects if compared to the other forms that it can be administered (such as nasal spray or oral tablet). since you said a 'shot' and you said that a nurse have had to be involved in, I can assume that you've been given it in injection form (since a nurse isn't needed for you to take a tablet or use it as nasal spray). I just hope that your symptoms that you are describing are going to subside in some time soon, however if you start noticing that they are not and they are continuing or maybe even getting worse then I would surely go back to the doctor and ask for another medication.
these are some of the most common side effects that are reported by patients using Toradol, you've got to check them with your doctor if they are persistent or they are becoming worse and worse: headaches, diarrhea, mild stomach pain or upset, constipation, drowsiness, gas, dizziness, stomach fullness, indigestion, vomiting, nausea or pain at the injection site. again, these are only the most common side effects - there might be others as well. having that said, you really should search for immediate medical help in case any of the following severe side effects are appearing in the time you use Toradol: one or multiple allergic reactions (allergic reactions are: difficulty breathing, itching, rash, hives, tightness in chest, unusual hoarseness, swelling of the mouth, tongue, lips or/ and face), chest pains, fever, child or persistent sore throat, bloody or black, tarry stools, cloudy or bloody urine, some unusual change in the amount of the urine produced or some trouble urinating, dark urine, depression, hallucinations, confusion, fainting, mouth sores, ringing in the ears, severe headaches or severe dizziness, fast or irregular heartbeats, one sided weakness, mental or mood changed, either red, swollen, peeling or blistered skin, severe vomiting or diarrhea, shortness of breath, severe or persistent stomach pain or severe nausea, persistent flu like symptoms, severe vomiting or diarrhea, swelling of the hands, arms, legs or feet, numbness of an arm or an leg, seizures, sudden or unexplained weight gain, unusual tiredness or weakness, vomit that it is looking like coffee grounds, unusual bruising or unusual bleeding, vision or speech changes, yellowing of the skin or eyes or also unusual joint or muscle pains.
all of the previous side effects that I have posted are covering MOST of the possible side effects, however this is still not the full list of side effects that can possible appear when using toradol. having that said, if you start noticing absolutely anything unusual/ different/ as it should not be etc. etc. while using the drug, you need to go to your doctor. if you have any other questions about side effects you should do the same.
talking about each side effect in particular and what it can affect…
Gastrointestinal: exactly as with any other non steroidal anti inflammatory substance, the gastrointestinal complaints are pretty common along patients that are on Toradol (ketorolac) therapy. even though, typically these side effects are mild in nature, some pretty serious gastrointestinal effects are still reported, even including colonic and peptic ulceration as well as gastrointestinal bleeding and perforation. the serious gastrointestinal bleeding may not be preceded by symptoms. even though the experience is being limited here, there are some clear indications that there are some risks of getting severe gastrointestinal effects which is increasing with a prolonged use of the toradol treatment. this is the reason why usually, toradol it is given for a short term management of pain, or that's what is the way it is being advised.
Respiratory side effects. respiratory side effects are few and they are not often reported, but they still might appear, they include: asthma, pulmonary edema, wheezing as well as dyspnea.
Dermatologic side effects are including rash, urticaria as well as pruritus. there are also some cases when exfoliative dermatitis have been reported too.
Hematologic side effects are including: increased bleeding time, thrombocytopenia, eosinophilia, inhibition of platelet aggregation, purpura, leukopenia as well as epistaxis.
Renal side effects. Renal side effects are being considered to be the most common/ severe and often experienced side effects with patients on toradol treatment. acute renal failure has been reported even with short term usage of the medication and even with moderate dosages. quite often, the hyperkalemia it is often accompanies with acute renal failure as well. a chronic and continous toradol therapy may end up in transient increases in BUN as well as creatinine in 2 % to about 3 % of patients taking it. there have been some animal studies done which has ended up in renal papillary necrosis after the animals have been exposed to chronic ketorolac use. it is considered that this might happen to humans as well.
the renal failure that it associated with hemolytic uremic syndrome has been developed in a 58 years old woman who was treated for arthralgias with the oral toradol. after a total dosage of 30 mg, the patient has developed vomiting as well as bloody diarrhea. then, 3 days later, the patient again has developed vomiting, nausea, facial as well as peripheral edema, oliguria and hypertension. when has been done an laboratory evaluation, they have also noticed: elevated lactate dehydrogenase, renal failure, hemolytic anemia, decreased fibrinogen and thrombocytopenia too. the treatment has been consisted of furosemide as well as supportive care and one week later, all of the laboratory numbers have been back within the normal ranges and the patient has been feeling well.
Those patients that are having pre existing renal diseases, hypovolemia, nephrotic syndrome, congestive heart failure, hepatic cirrhosis or hypoalbuminemia are under an increased risk of having acute renal failure during the toradol treatment and that's due to the fact that renal function in those conditions are depending upon renal prostaglandin synthesis. in such kind of situations, risk versus benefit really need to be very carefully weighed by a professional doctor!
in addition to that, ketorolac also may have some renal metabolic effects like for example salt and water retention, hyperkalemia and also inhibition of diuretic action because of the suppression of the renin angiotensin - aldosterone system. these are the effects that are pretty similar to those that are reported with other non steroidal anti inflammatory agents as well and that's since they are all acting pretty much the same with some slight differences.
also, there is a case control study who has suggested that those patients who has taken 5000 or even more pills that are containing NSAIDs during their entire life then they may be at an increased risk of an end stage renal disease. those renal side effects have also included acute renal failure and flank pain. hematuria, oliguria, nephritis, proteinuria, hyperkalemia as well as urinary frequency has also been reported! besides that, ketorolac has also been reported to be implicated in a case of hemolytic uremic syndrome as well.
there are also hepatic side effects which are pretty common as well, they have included borderline increases in liver function tests in up to approximately 15% or so of the patients in clinical trials. but anyway, some significant increases (which is considered to be like 3 times the normal values) are occurring in less than only 1 % of the patients. liver failure, cholestatic jaundice as well as hepatitis have also been reported in the time of post marketing experience.
the psychiatric side effects also can occur and among them are: depression, abnormal dreams (vivid dreams, nightmares etc.), insomnia as well as nervousness.
Cardiovascular side effects: the non steroidal anti inflammatory drugs (NSAIDs) are able to elevate blood pressure and therefore to increase the risk of the initiation of antihypertensive therapy. besides that, the NSAIDs may also antagonize the blood pressure which is lowering effect of antihypertensive medications in those patients that are already being treated with the antihypertensive drugs. among the cardiovascular side effects are included: palpitations, hypotension, edema, pallor, vasodilation as well as syncope. in addition to that, blood pressure also may be elevated by this medication which may have clinical relevance in those patients with the comorbid illnesses.
Nervous system side effects are common among patients on toradol as well, they are including: headache (approx. 17 %), dizziness (3 % to 9%), drowsiness or somnolence (also between 3% and 9%), tremors, hallucinations, convulsions, vertigo as well as euphoria. besides all of these, there is also reported stupor, hyperkinesia and paresthesias, however the causality it is unknown.
There are also ocular side effects but they are very rare. ocular side effected are altered or blurred vision and it has occurred in less than 1 % of patients.
About hypersensitivity side effects they have included: bronchospasm, fever, anaphylaxis and acute angioedema (here including laryngeal as well as tongue edema). in addition to that, there have also been reported the following side effects: bulluous reactions like for example Stevens Johnson syndrome, erythema multiforme, toxic epidermal necrolysis as well as Lyell's syndrome.
The local side effects that are being associated with intramuscular injection of the toradol are including: local pain, bruising, hematoma, ecchymosis as well as tingling.
in the end, there are also other side effects which has included very rare reports of hearing loss as well as tinnitus. plus to that, weight gain in the time of the long term usage of toraol has been reported as well.
I really hope very much that this is going to give you some insight about your situation and it would be helpful. I do understand what you've tried to say when said that you want to know as much as possible about a drug before taking it. I honestly think that this is the best idea. good luck to you and just let us know how things are turning out for you!