Amitriptyline HCL

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Amitriptyline HCL is an antidepressant with sedative, analgesic and anti-ulcer effect. One way to save money on the Amitriptyline HCL retail cost regardless of income and insurance status is to use Amitriptyline HCL coupons or discount cards from RXCoupons. Use our Amitriptyline HCL coupons at your online pharmacy and receive up to 75% off the sale price each time you refill your prescription.

Amitriptyline HCL guide

Amitriptyline HCL is an antidepressant with sedative, analgesic and anti-ulcer effect. It reduces appetite and helps prevent urinary incontinence. Amitriptyline HCL is also used in the treatment of bulimia nervosa (with or without depression). The active ingredient of the drug is Amitriptyline Hydrochloride. This medication is prescribed to treat different types of depressive disorders, including depressions caused by alcohol abuse and depressions accompanied by sleep disturbances, agitation, anxiety.

Amitriptyline HCL main indications for use

Amitriptyline is used in schizophrenic psychosis, mixed emotional disorders, nocturnal enuresis, bulimia nervosa. It also helps to treat chronic pain (headache, migraine, atypical facial pain, pain in cancer patients, posttraumatic and diabetic neuropathy, rheumatic pain, postherpetic neuralgia). Amitriptyline is also used for ulcerative gastrointestinal diseases. The drug is effective in reducing pain in rheumatic diseases, cancer, atypical facial pain, migraine, etc.

In what cases Amitriptyline is contraindicated

Amitriptyline is contraindicated in conduction disturbances in myocardial infarction, severe hypertension, acute kidney and liver failure, atony of the bladder, prostatic hypertrophy. It should not be used in case of hypersensitivity, during pregnancy and lactation, in children under 6 years old. Do not use Amitriptyline 2 weeks before starting treatment with MAO inhibitors. Caution must be exercised in elderly people and during pregnancy, especially in the 1st trimester. The drug may pass into breast milk and cause drowsiness in children.

Amitriptyline HCL dosage information

Amitriptyline tablets should be swallowed without being chewed. The starting dose for adults is 25-50 mg. The tablets should be taken just before bedtime. The dosage may be gradually increased to 150-200 mg per day, used in 3 divided doses. The dosage should be increased to 300 mg per day if there is no improvement within 2 weeks after starting Amitriptyline therapy. If symptoms of depression disappear, the dosage should be reduced to 50-100 mg per day. If the patient's condition does not improve within 3-4 weeks after starting the therapy, further treatment regimen is considered inappropriate.

The daily dose in neurological pain (including chronic headaches, migraine) is up to 100 mg. Children (6-10 years) with nocturnal enuresis should take 10-20 mg per day, before bedtime.

What are the side effects of Amitriptyline HCL?

Amitriptyline therapy may cause blurred vision, dry mouth, high eye pressure, high body temperature, constipation, functional intestinal obstruction. Usually, all these side effects disappear soon after dose reduction.

In addition, the following effects may occur with Amitriptyline therapy: weakness, drowsiness, fatigue, insomnia, dizziness, irritability, tremor, hallucinations, paresthesia, convulsions, arrhythmia and tachycardia, nausea, heartburn, stomatitis, vomiting, epigastric discomfort, diarrhea, jaundice, pruritus, hair loss.

Amitriptyline HCL overdose

In case of overdose patients may have symptoms of fever, drowsiness, disorientation, shortness of breath, dysarthria, agitation, hallucinations, seizures, coma, vomiting, heart failure, arrhythmia, hypotension. In case of overdose patients should stop taking the drug (gastric lavage may be attempted).

Special instructions for Amitriptyline therapy

Amitriptyline therapy may be combined with neuroleptic drugs or benzodiazepine. Patients who are in severe depressive states require constant medical supervision for early control and detection of suicidal tendencies.

It is necessary to tell the surgeon that you are taking Amitriptyline before having an operation (with local or general anesthesia). Chronic administration of Amitriptyline may increase the incidence of dental caries.

Amitriptyline should be taken with caution in patients with bronchial asthma, manic-depressive illness, alcoholism, epilepsy, hyperthyroidism, angina, heart failure, angle-closure glaucoma, schizophrenia. Patients should not be allowed to drive or work in potentially dangerous situations that require high concentration of attention. Do not drink alcohol during Amitriptyline treatment.

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