Nucynta (tapentadol) Coupons, Discounts & Cost
Nucynta (tapentadol) is used for the treatment of neuropathic pain. One way to save money on the Nucynta retail cost regardless of income and insurance status is to use Nucynta coupons or discount cards from RXCoupons. Use this Tapentadol coupon at this online pharmacy and receive up to 75% off the sale price.
Nucynta pharmacologic effect
Nucynta (tapentadol) is used for the treatment of neuropathic pain. This is an opioid analgesic that is used twice a day to treat neuropathic pain in adults with peripheral neuropathy associated with diabetes. In addition, Nucynta is approved for the treatment of chronic pain syndrome of medium and high intensity in adults. It can be used for a long period of time.
Tapentadol has an analgesic effect. It is effective in patients suffering from pain of neuropathic, visceral genesis, as well as pain caused by certain inflammatory processes (back pain, oncological and non-oncological pain).
What should I know about Nucynta contraindications?
Standard contraindications: - hypersensitivity to tapentadol; - signs and symptoms of intestinal obstruction (paralytic ileus); - acute intoxication with alcohol, hypnotics, central analgesics and psychotropic drugs; - patients with respiratory depression, as well as patients with severe bronchial asthma or hypercapnia; - patients using monoamine oxidase inhibitors; - severe renal insufficiency; - severe hepatic insufficiency; - lactose intolerance, glucose-galactose malabsorption; - patients up to 18 years of age.
Caution is recommended for patients having symptoms of lung problems.
Nucynta is not recommended for patients with low blood pressure, acute pancreatitis, hepatic insufficiency of moderate severity, intracranial injury, convulsive syndrome or certain conditions that increase the risk of seizures;
It is recommended to reduce the dose of Nucynta when using it with serotonergic drugs.
Nucynta tablets dosage and administration
As with other analgesics, the dose of the drug should be selected individually in accordance with the severity of pain syndrome. Nucynta should be taken twice a day, approximately every 12 hours, regardless of food intake. Each tablet should be taken with a sufficient amount of liquid (avoid chewing or breaking).
Patients who do not take narcotic analgesics should start Nucynta therapy with a dose of 50 mg twice a day.
Maintenance therapy: the dose should be selected individually and under careful supervision of your doctor.
You can increase the dose of tapentadol by 50 mg every 3 days. This will be sufficient to achieve adequate pain control in most patients.
The daily dose of tapentadol should be under 500 mg.
It is recommended to gradually reduce the dose of the drug in order to avoid tapentadol withdrawal syndrome.
Adults with chronic diseases
Patients with mild or moderate renal failure should not reduce the dose.
Tapentadol is contraindicated in patients with severe renal dysfunction.
Patients with mild hepatic impairment should not reduce the dose.
Care must be taken when prescribing Nucynta to patients with moderate hepatic impairment: they should begin with 50 mg of tapentadol once a day.
Tapentadol is contraindicated in patients with severe hepatic impairment.
In general, the recommended doses for elderly patients are the same as for middle-aged patients with normal kidney and liver function. Nevertheless, elderly patients are more likely to have side effects. Therefore, care should be taken when choosing Nucynta dose for elderly patients.
The drug is contraindicated for use in patients under the age of 18.
What are the side effects for Nucynta?
Approximately 60% of patients who took the drug had mild or moderate side effects. The most common symptoms include: nausea, dizziness, constipation, headache and drowsiness.
Metabolism: decreased appetite, weight loss
CNS: sleep disorders, unusual dreams, anxiety, excitability, anxiety, psychomotor agitation, confusion, euphoria, dizziness, headache, drowsiness, tremors, attention disorders, syncope, memory impairment, convulsions
Cardiovascular system: palpitations, low blood pressure.
Respiratory system: dyspnea.
Digestive system: nausea, constipation, vomiting, diarrhea, indigestion, discomfort in the abdomen.
Skin and subcutaneous tissues: itching, hyperhidrosis, rash hives.
Kidneys and urinary tract: urination problems.
Other disorders: sexual dysfunction, fatigue, edema.
Nucynta special instructions
Combination therapy with benzodiazepines, barbiturates and opioids (analgesics or antitussive drugs) can increase the risk of respiratory depression. CNS depressants (including alcohol) can increase the sedative effect of tapentadol.
Caution should be exercised while using tapentadol with mu-opioid receptor agonists and antagonists. Careful monitoring of side effects such as respiratory depression is necessary.
Simultaneous application with ketoconazole, fluconazole and meclofenamic acid should be avoided.
Patients should be careful while taking rifampicin, phenobarbital and St. John's Wort preparations. Such combination can increase the risk of side effects.
Tapentadol is contraindicated in patients taking monoamine oxidase inhibitors. Such combination can cause dangerous side effects.
Tapentadol therapy can provoke respiratory depression (dose-dependent). For this reason, patients with respiratory function impairment should use Nucynta with caution and in minimal effective doses.
Tapentadol should not be prescribed for patients with increased intracranial pressure or coma. The drug should be used with caution in patients with craniocerebral trauma and brain tumors.
Nucynta warnings
Store at temperatures not higher than 30° C.