Daivonex (calcipotriol) Coupons, Discounts & Cost
Daivonex (calcipotriol) is an effective non-hormonal drug with antiproliferative activity. One way to save money on the Cytoxan (cyclophosphamide) retail cost regardless of income and insurance status is to use Cytoxan (cyclophosphamide) coupons or discount cards from RXCoupons. Use our Cytoxan (cyclophosphamide) coupons at your online pharmacy and receive up to 75% off the sale price each time you refill your prescription.
What is Daivonex (calcipotriol)?
Daivonex (calcipotriol) is an effective non-hormonal drug with antiproliferative activity. The active substance is calcipotriol, which is a biologically active vitamin D metabolite analogue. Calcipotriol can block specific immune mediators. Daivonex cream is indicated for the treatment of psoriasis vulgaris (including severe scalp psoriasis) as monotherapy and in the complex treatment of patients with psoriasis (combined therapy with cyclosporine, corticosteroids, acitretin).
Contraindications for Daivonex (calcipotriol)
The drug is not used for the treatment of patients with hypersensitivity to the drug. It is not used during pregnancy and breastfeeding.
Do not use this cream in patients with the diseases caused by violation of calcium metabolism.
Age restrictions: patients up to 6 years.
Caution should be used in acute renal and hepatic failure, hypercalcemia, hypervitaminosis D, hypercalciuria, as well as in patients older than 65 years.
Daivonex (calcipotriol) dosage
Daivonex (calcipotriol) cream should be applied 2 times a day (no more than 6-8 weeks). The maximum daily dose of the cream should not exceed 15 g (100 g for weekly dose). If necessary, you can apply the cream only 1 time per day.
The maximum weekly dose in the treatment of children: from 6 to 12 years - 50 g, over 12 years - 75 g. Clinical improvement should occur within 7-14 days after starting treatment.
The cream is well tolerated in combination with cyclosporine, acitretin or corticosteroids, as well as with physical therapy. The recommended regimen for combined therapy with corticosteroids: apply Daivonex in the morning, while corticosteroids - in the evening.
Common and rare Daivonex (calcipotriol) side effects
In some cases, Daivonex (calcipotriol) cream can cause skin irritation, hypercalcemia. Metabolism: very rarely - hypercalciuria, hypercalcemia. Immune system: very rarely - urticaria, allergic reactions, angioedema. Dermatological reactions: often - itching, skin irritation, rash, dryness of the skin, erythema; rarely - worsening of psoriasis symptoms, eczema; very rarely - reversible depigmentation, hyperpigmentation, periorbital edema, photosensitivity. In addition, the cream can cause contact dermatitis. The most typical reactions: local skin irritation. Common reactions: erythema, itchy skin. Atypical reactions: dermatitis, exacerbation of psoriasis. Very rare reactions: hyperpigmentation, hypercalciuria, hypercalcemia. There are cases of photosensitivity and hypersensitivity reactions including very rare cases of angioedema and facial edema.
Daivonex should not be used together with drugs containing salicylic acid (for topical application).
Precautions for Daivonex (calcipotriol)
Daivonex (calcipotriol) cream should never be applied to your face. You must wash your hands thoroughly to avoid accidental contact of the product with the skin. The cream should not be applied to large areas of skin (exceeding 30% of the body surface).
Do not exceed the recommended dosage of calcipotriol. In case of overdose, patients may experience the following symptoms: fatigue, constipation, thirst, decreased muscle tone. You may need to stop using the drug in case of overdose.
Patients are advised to avoid excessive exposure to direct sunlight during treatment. Patients under the age of 18 years may use the cream only on small areas of the skin. Daivonex does not affect the patient's ability to drive safely.
Calcipotriol should not be used with salicylic acid solution.
Daivonex (calcipotriol) storage conditions
Store at temperatures below 25° C. Keep out of the reach of children.