Depo-Medrol (methylprednisolone) Coupons, Discounts & Cost
Depo-Medrol is a drug from the group of corticosteroids (adrenocortical hormones) used to treat almost all diseases of internal organs, including the spinal column. One way to save money on the Depo-Medrol (methylprednisolone) retail cost regardless of income and insurance status is to use Depo-Medrol (methylprednisolone) coupons or discount cards from RXCoupons. Use our Depo-Medrol (methylprednisolone) coupons at your online pharmacy and receive up to 75% off the sale price each time you refill your prescription.
Depo-Medrol (methylprednisolone) - what it is?
Depo-Medrol is a drug from the group of corticosteroids (adrenocortical hormones) used to treat almost all diseases of internal organs, including the spinal column. The active substance of the drug is methylprednisolone.
Depo-Medrol synthetic glucocorticoid has a pronounced anti-inflammatory, anti-allergic and immunosuppressive activity.
Depo-Medrol (methylprednisolone) main indications
For intramuscular administration: - Primary, secondary and acute adrenal insufficiency; - Congenital adrenal hypoplasia; - Hypercalcemia (caused by a tumor); - Purulent thyroiditis; - Congenital adrenal hyperplasia; - Combination therapy in rheumatic diseases, including rheumatoid arthritis, acute rheumatic endocarditis, osteoarthritis, acute and subacute bursitis, tenosynovitis, acute gouty arthritis, psoriatic arthritis, ankylosing spondylitis; - Collagen diseases; - Systemic dermatomyositis; - Severe skin diseases, such as pemphigus, severe erythema multiforme, exfoliative dermatitis, dermatitis herpetiformis, severe seborrheic dermatitis, severe psoriasis; - Severe allergic diseases, including asthma, severe contact dermatitis, severe atopic dermatitis; - Severe allergic and inflammatory processes in the eye, including iritis, iridocyclitis, chorioretinitis, optic neuritis, corneal ulcers, keratitis; - Combination therapy in the acute phase of ulcerative colitis and regional enteritis; - Respiratory diseases, including symptomatic sarcoidosis, berylliosis, pulmonary tuberculosis (simultaneously with chemotherapy), Loeffler's syndrome; - Hematologic diseases: autoimmune hemolytic anemia, secondary thrombocytopenia in adults, congenital hypoplastic anemia, palliative therapy in leukemia and lymphomas.
For synovial fluid or soft tissue: - Adjuvant therapy in acute synovitis, rheumatoid arthritis, gouty arthritis, epicondylitis, post-traumatic osteoarthritis.
For other purposes: - Keloids, psoriatic plaques, granuloma annulare, neurodermatitis, discoid lupus erythematosus, necrobiosis lipoidica, alopecia areata.
How to use Depo-Medrol (methylprednisolone)
The recommended dose depends on the severity of the disease.
Joints: the usual dose is 20-80 mg. It is important to make the injection into the synovial space. The course is 1-4 injections (individual intervals). Adrenogenital syndrome: 40 mg every 2 weeks. Rheumatoid arthritis: 40-120 mg weekly. Skin diseases: 40-120 mg weekly, for 1-4 weeks. Severe acute dermatitis: 80-120 mg. The effect occurs within 8-12 hours. Chronic contact dermatitis: repeated injections are possible at intervals of 5-10 days. Seborrheic dermatitis: 80 mg weekly. Bronchial asthma: 80-120 mg. The effect occurs within 6-48 hours and lasts from several days to 2 weeks. Allergic rhinitis: 50-120 mg. The effect occurs within 6 hours and lasts from a few days up to 3 weeks. Ulcerative colitis: the drug is administered into the rectum at a dose of 40-120 mg. Pediatric dose should be reduced according to the patient’s age and body weight. The dose also depends on the severity of the condition. Patients should not try any kind of vaccination and immunization during treatment (high risk of neurological complications).
Depo-Medrol (methylprednisolone) possible side effects
Endocrine system: reduction of glucose tolerance, adrenal suppression, Cushing's syndrome (moon face, obesity, hirsutism, high blood pressure, dysmenorrhea, amenorrhea, myasthenia gravis). Digestive system: nausea, vomiting, pancreatitis, stomach ulcers, erosive esophagitis, bleeding and perforation of the gastrointestinal tract, increased or decreased appetite, flatulence, hiccups. Cardiovascular system: arrhythmia, bradycardia (up to cardiac arrest), high blood pressure, thrombosis. Patients with acute and subacute myocardial infarction - necrosis. Nervous system: delirium, disorientation, euphoria, hallucinations, bipolar disorder, depression, paranoia, increased intracranial pressure, nervousness or anxiety, insomnia, dizziness, vertigo, headache, convulsions. Metabolism: hypocalcemia, increased body weight, sweating. Musculoskeletal system: osteoporosis (very rare - pathological fractures), loss of muscle mass. Other reactions: high eye pressure, bacterial, fungal or viral eye infections, trophic changes of the cornea, fluid retention, hypernatremia, hypokalemia, arrhythmia, myalgia or muscle spasm, unusual weakness and fatigue.
Depo-Medrol (methylprednisolone) special instructions
In case of active tuberculosis process, Depo-Medrol may be used only in conjunction with anti-tuberculosis therapy.
Depo-Medrol is ineffective in septic shock. Methylprednisolone cannot be used for replacement therapy in Addison's disease.
Be particularly careful when using Depo-Medrol in patients with severe hypertension and chronic heart failure.
Patients with diabetes should monitor blood glucose concentration.