Precose (acarbose) Coupons, Discounts & Cost
Precose (acarbose) is a medicinal product for oral administration, which has a hypoglycemic effect. One way to save money on the Precose retail cost regardless of income and insurance status is to use Precose coupons or discount cards from RXCoupons. Use this Acarbose coupon at this online pharmacy and receive up to 75% off the sale price.
What is Precose?
Precose (acarbose) is a medicinal product for oral administration, which has a hypoglycemic effect. It is usually used during meals (with carbohydrates). Acarbose reduces the concentration of glucose in the blood after ingestion.
The drug acts in the lumen of the small intestine. It helps reduce the concentration of glucose in the intestine, and thus reduce its absorption. The drug does not increase the susceptibility of cells to insulin, so it can not cause hypoglycemia.
About 35% of the dose is absorbed from the gastrointestinal tract. The maximum concentration is achieved in 1 hour. It is absorbed exclusively in the gastrointestinal tract.
The main side effect (in about 75% of patients) is flatulence, so it makes sense to adjust the dose gradually. Precose cannot be used by patients who have any gastrointestinal diseases (for example, gastroparesis).
Acarbose indications: diabetes mellitus type 2 in case of ineffectiveness of diet therapy, diabetes mellitus as part of combination therapy, prevention of diabetes mellitus type 2 (in patients with impaired glucose tolerance in combination with diet and exercise).
Precose contraindications
Precose is contraindicated in the following conditions: chronic and inflammatory bowel disease, ulcerative bowel disease with severe digestion and absorption disorders, Roemheld syndrome, ventral hernias, intestinal obstruction (complete, partial, in predisposed patients), other conditions associated with flatulence, impaired liver function, pregnancy, lactation, hypersensitivity to acarbose.
Use with caution in the following conditions: fever, infection, injuries, pre- and postoperative period (the therapy is possible only if the expected positive effect exceeds the potential risk).
Precose dosage information
The starting dose is 50 mg 3 times a day. Increase the dose to 100-200 mg 3 times a day every 4-8 weeks.
The maximum daily dose is 600 mg per day. The maximum single dose is 200 mg.
Prevention: the initial dose is 50 mg once a day with a gradual increase to 100 mg.
Precose side effects
Possible side effects from the gastrointestinal tract: abdominal pain, flatulence, nausea, diarrhea. These effects are dose-dependent. Therefore, a gradual increase in the dose is recommended. More serious side effects: intestinal obstruction, jaundice, hepatitis.
Allergic reactions: skin rash, hyperemia, exanthema, urticaria.
Other: rarely - swelling.
Precose overdose
Symptoms: discomfort in the abdominal area, diarrhea, flatulence.
Treatment: exclude from the diet food and beverages containing carbohydrates (for 4-6 hours).
Precose interactions
Acarbose reduces digestibility and concentration of digoxin.
Acarbose may increase the risk of hypoglycemia when used in conjunction with hypoglycemic agents.
Neomycin may increase the side effects caused by acarbose therapy.
Substances that can reduce the effect of acarbose: calcium channel blockers, corticosteroids, digestive enzyme preparations (pancreatin, amylase), isoniazid, nicotinic acid, estrogen, oral contraceptives, sympathomimetics, thiazides and other diuretics, hormones of the thyroid gland.
Precose special instructions
One should follow a diet for patients with diabetes. Foods high in carbohydrates can cause intestinal disturbances.
Simultaneous use of acarbose with sulfonylurea derivatives, metformin or insulin may lead to a more pronounced hypoglycemic effect.
It is not recommended to take acarbose simultaneously with alcohol.
It is forbidden to use this preparation during pregnancy and lactation.
Acarbose is contraindicated for use in children under 18 years of age.
Acarbose should be stored at room temperature, out of the reach of small children.