Remeron (mirtazapine) Coupons, Discounts & Cost
Remeron is a tetracyclic antidepressant with predominantly sedative effect. One way to save money on the Remeron retail cost regardless of income and insurance status is to use Remeron coupons or discount cards from RXCoupons. Use this Mirtazapine coupon at this online pharmacy and receive up to 75% off the sale price.
What should you know about Remeron?
Remeron is a tetracyclic antidepressant with predominantly sedative effect. This drug is used to treat depression.
Remeron contraindications include: - Patients up to 18 years of age; - Lactose intolerance, lactase deficiency, glucose-galactose malabsorption; - Lactation; - Hypersensitivity to any component of the drug.
Use with caution: - Epilepsy; - Renal and hepatic impairment; - Heart diseases (angina pectoris, myocardial infarction); - Cerebrovascular diseases (including ischemic stroke); - Arterial hypotension; - Drug dependence; - Mania and hypomania; - Violations of urination, including hyperplasia of the prostate; - Diabetes; - Acute angle-closure glaucoma, high eye pressure; - Combination therapy with benzodiazepines; - Pregnancy (if the expected benefit exceeds the possible risks).
How to use Remeron
Swallow the tablets whole with liquid (if necessary). The recommended initial dose is 15-30 mg. The effective daily dose is determined individually. The effect of the drug can be reduced in patients with hepatic and renal insufficiency.
You can take Remeron 1 time per day, preferably at the same time, in the evening before bedtime. It is also possible to divide the daily dose into 2 parts - the lowest dose is taken in the morning and the highest is taken at night.
The duration of treatment is usually 4-6 months (until the symptoms of depression disappear completely). After that, the dose is gradually reduced (until the drug is completely discontinued). The maximum allowable daily dose is 45 mg. Treatment should be discontinued if no improvement is observed within 2-4 weeks.
Remeron side effects
Nervous system: very often - drowsiness (usually in the first weeks of treatment), headache, sedation; often - tremor, dizziness, lethargy; rarely - syncope, paresthesia; very rarely - serotonin syndrome, seizures (stroke).
Blood and lymphatic system: agranulocytosis, aplastic anemia, granulocytopenia, thrombocytopenia, eosinophilia.
Musculoskeletal system: often - back pain, arthralgia, myalgia.
Gastrointestinal tract: very often - dry mouth; often - diarrhea, nausea, vomiting; rarely - edema of the oral mucosa.
Metabolism: very often - increased appetite, weight gain.
Skin and subcutaneous tissues: often - skin rash.
Other: often - edema, fatigue, insomnia, anxiety; rarely - akathisia, hyperkinesia, agitation, mania, nightmares, hallucinations, suicidal behavior.
Remeron warnings
It should be borne in mind: the depressive phase of manic-depressive psychosis can be transformed into a manic phase in some patients. Elderly people are usually more sensitive to the drug (especially with regard to side effects).
Antidepressants increase the risk of suicidal thoughts and behavior in young people under the age of 24 with mental disorders or depression. Therefore, the drug should be administered after a thorough evaluation of the risk-benefit ratio.
Low doses may decrease the effectiveness of Remeron. The therapy should be stopped in case of signs of jaundice. It is recommended to avoid drinking alcohol during treatment.
The patient should see a doctor if he has symptoms such as sore throat, stomatitis, fever and other signs of flu-like syndrome.
Long-term treatment may lead to such symptoms as anxiety, agitation, headache, dizziness, nausea. It is recommended to cancel the drug gradually.
Drug interactions
Remeron should be used with caution with HIV protease inhibitors, ketoconazole, azole antifungal agents, nefazodone, erythromycin.
Cimetidine may increase the bioavailability of mirtazapine by more than 50%. Therefore, a reduction in the dose of Remeron may be required.
Mirtazapine should not be administered concomitantly with monoamine oxidase inhibitors.
Remeron can enhance the sedative effect of benzodiazepines and other sedatives, as well as the effects of alcohol.