Revlimid (lenalidomide) Coupons, Discounts & Cost
The active substance of Revlimid is lenalidomide. One way to save money on the Revlimid retail cost regardless of income and insurance status is to use Revlimid coupons or discount cards from RXCoupons. Use this Lenalidomide coupon at this online pharmacy and receive up to 75% off the sale price.
Revlimid indications for use
The active substance of Revlimid is lenalidomide. This drug belongs to the pharmacological group of immunomodulating agents. It is used in the complex therapy of multiple myeloma.
Revlimid works to suppress the production of tumor necrosis factor. In addition, it activates the growth of T lymphocytes.
The standard dosage of Revlimid is 25 mg once a day for 3 weeks. Then there is a one-week break before the course is repeated. Revlimid therapy does not depend on the time of ingestion. The capsule should be swallowed whole with water.
Elderly patients
No special clinical studies have been conducted to evaluate the pharmacokinetics of lenalidomide in elderly patients. Caution should be exercised when selecting the dose of the drug (high risk of impaired renal function in the elderly).
Patients with impaired renal function
Lenalidomide is excreted mainly by the kidneys. In this regard, the risk of toxic reactions may be higher in patients with impaired renal function.
Patients with mild renal insufficiency should not change the dose of Revlimid.
What are the possible contraindications?
Revlimid is contraindicated in case of allergic reactions to lenalidomide or any other components that are part of Revlimid, lactose intolerance or lactase insufficiency. It should not be used during pregnancy and lactation, as well as in patients under 18 years of age.
Use with caution in the elderly, in patients with renal insufficiency or liver failure, as well as in patients with deep vein thrombosis.
Do not take Revlimid together with drugs that increase the risk of thrombosis and drugs used for hormone replacement therapy.
Possible contraindications during pregnancy and lactation
Lenalidomide is a structural analogue of thalidomide, which can cause birth defects. It is known that thalidomide causes severe life-threatening violations of the internal organs of the fetus. Therefore, the risk of congenital defects is very high if Revlimid is used during pregnancy.
Women of reproductive age should be treated with effective methods of contraception during Revlimid therapy. Lenalidomide should be discontinued if a woman is pregnant.
Breastfeeding
Breastfeeding should be discontinued during Revlimid therapy.
Revlimid side effects
Patients taking Revlimid should be informed of potential side effects: infections of the upper respiratory tract, iron deficiency anemia, thrombocytopenia, neutropenia and leukopenia, hypothyroidism, dizziness, headaches, visual impairment and cataract, tinnitus and hearing loss, heart rhythm disturbances, thromboses, dyspnea, nasal and gastrointestinal bleeding, disorders of digestion and abdominal pain, nausea, vomiting, skin rash, hives, excessive sweating, muscle cramps, joint and bone pain, erectile dysfunction, edema, flu-like syndrome.
Infectious and parasitic diseases: very often - pneumonia, upper respiratory tract infections; often - sepsis, bacterial, viral and fungal infections (including opportunistic infections), sinusitis.
Benign, malignant neoplasms (including cysts and polyps): rarely - basal cell carcinoma.
Blood and lymphatic system: very often - thrombocytopenia, neutropenia, anemia, hemorrhagic disorders, leukopenia; often - pancytopenia; rarely - autoimmune hemolytic anemia, hemolytic anemia, coagulopathy.
Immune system: rarely - hypersensitivity reactions.
Endocrine system: often: hypothyroidism, hyperthyroidism.
Metabolism: very often - hypokalemia, decreased appetite; often - hypomagnesemia, hypocalcemia, hypophosphatemia.
Nervous system: very often - peripheral neuropathy, dizziness, tremor, headache; often - ataxia, stroke, dizziness, fainting; rarely - intracranial hemorrhage, transient ischemic attack.
Cardiovascular disorders: often - atrial fibrillation, bradycardia; rarely - arrhythmia, atrial flutter, myocardial infarction, congestive heart failure, tachycardia.
Vascular disorders: very often - thromboembolic disorders (deep vein thrombosis and pulmonary embolism); often - arterial hypotension, ecchymosis; rarely - ischemia, peripheral ischemia.
Respiratory system: very often - shortness of breath, nasopharyngitis, pharyngitis, bronchitis; often - respiratory distress syndrome; rarely - interstitial pneumonitis.
Gastrointestinal tract: very often: constipation, diarrhea, nausea, vomiting; often - gastrointestinal bleeding, abdominal pain, dry mouth, stomatitis, dysphagia; rarely - colitis, pancreatitis.
Learn about interaction with other drugs
Revlimid is not used with erythropoietic agents, digoxin and oral contraceptives.
Storage conditions
Store the drug at a temperature of no more than 25° C.