Seroflo (fluticasone/salmeterol) Coupons, Discounts & Cost
Seroflo is a combined preparation with anti-asthmatic, bronchodilating, anti-inflammatory effect. One way to save money on the Seroflo retail cost regardless of income and insurance status is to use Seroflo coupons or discount cards from RXCoupons. Use this Fluticasone/Salmeterol coupon at this online pharmacy and receive up to 75% off the sale price.
Seroflo pharmacological action
Seroflo is a combined preparation with anti-asthmatic, bronchodilating, anti-inflammatory effect. Salmeterol prevents bronchospasm, while fluticasone improves pulmonary function and suppresses inflammation.
Salmeterol is effective for the prevention of histamine-induced bronchospasm. It helps reduce bronchial hyperresponsiveness. Salmeterol has no effect on the cardiovascular system when used in therapeutic doses. Studies have shown that salmeterol effectively suppresses the reactions to inhaled allergens.
Fluticasone has a pronounced anti-inflammatory effect. It helps reduce the severity of symptoms of diseases accompanied by airway obstruction. Lower concentrations of fluticasone are observed in patients with bronchial asthma and chronic obstructive pulmonary disease. It is excreted through the gastrointestinal tract. Fluticasone therapy is not associated with unwanted side effects. Caution should be used when combining inhibitors of CYP3A4 and fluticasone.
Seroflo: indications for use
Seroflo is used for basic therapy of diseases associated with reversible airway obstruction (including bronchial asthma in children and adults). It is advisable to use combination therapy (bronchodilator and GCS). It is also used in patients who regularly use GCS for inhalations. Seroflo is also used for maintenance therapy in chronic obstructive pulmonary disease.
Seroflo: instructions for use
Seroflo should be used only for inhalations. The dose is determined by the doctor.
Patients should be warned that the drug should be used regularly, even in the absence of symptoms of the disease. Patients should be monitored regularly in order to select the optimal dose.
The initial dose is based on the dose of fluticasone. The initial dose of Seroflo should be gradually reduced to the lowest effective dose.
Adults and adolescents aged 12 years and older: Seroflo should be used twice a day (in two divided doses).
Children aged 4 to 12 years: Seroflo should be used once or twice a day (in two divided doses).
There is no need to reduce the dose in patients with impaired renal or hepatic function.
Seroflo overdose
Salmeterol overdose symptoms include tremor, headache and tachycardia. High doses of fluticasone may lead to a temporary suppression of adrenal function. However, long-term administration of fluticasone in doses exceeding the recommended levels can lead to suppression of adrenal function (mainly in children using excessively high doses of Seroflo for several months or years). Patients should know that Seroflo should not be taken in doses higher than recommended.
Seroflo: contraindications
Seroflo should not be used in case of hypersensitivity to the components of the drug. It is not prescribed to children up to 4 years of age.
Seroflo is used with caution: fungal, viral or bacterial infections of the respiratory system (including pulmonary tuberculosis), thyrotoxicosis, hypothyroidism, pheochromocytoma, diabetes, idiopathic hypertrophic subaortic stenosis, uncontrolled hypertension, arrhythmias, ischemic heart disease, angina, cataract, glaucoma, osteoporosis, pregnancy, breastfeeding.
Seroflo: side effects
Fluticasone effects:
Respiratory system: candidiasis of the oral cavity and pharynx, paradoxical bronchospasm.
Other reactions: rarely - allergic skin reactions, respiratory symptoms (bronchospasm).
Salmeterol effects:
Cardiovascular system: headache; rarely (in predisposed patients) - heart rhythm disturbances (including atrial fibrillation, supraventricular tachycardia).
Allergic reactions: rash, angioedema.
Other reactions: tremor, nervousness, arthralgia, nausea; rarely - muscle cramps, irritation of the mucous membranes.
Seroflo therapy: precautions
Seroflo is used for long-term treatment. It is recommended to rinse the mouth and throat with water after each inhalation.
The increased demand for short-acting bronchodilators indicates an exacerbation of the disease.
Sudden exacerbation of bronchial asthma is a life-threatening symptom. Therefore, in such situations, it is necessary to increase the dose of GCS.
Care should be taken when prescribing GCS to patients with pulmonary tuberculosis.
Seroflo should be used with caution in patients with hyperthyroidism.
Keep in mind that abrupt cessation of Seroflo therapy is always risky.