Videx EC (didanosine) Coupons, Discounts & Cost
Videx EC (didanosine) is an antiviral drug, which is active against HIV. One way to save money on the Videx EC retail cost regardless of income and insurance status is to use Videx EC coupons or discount cards from RXCoupons. Use this Didanosine coupon at this online pharmacy and receive up to 75% off the sale price.
General information about Videx EC
Videx EC (didanosine) is an antiviral drug, which is active against HIV. It has been proved that didanosine inhibits HIV replication in human cells.
Videx EC is used as a part of antiretroviral therapy in combination with other drugs that prevent HIV.
In what case you should not use Videx EC
Videx EC absolute contraindications: phenylketonuria, breastfeeding, hypersensitivity to didanosine or other components of the drug.
Videx capsules are contraindicated for children up to 3 years of age.
Videx EC should be used with caution in case of pancreatitis, progressive HIV infection, violations of kidney or liver function. Pregnant women should take this drug exclusively on strict indications. Breastfeeding should be interrupted.
How to take the drug
Videx capsules should be used on an empty stomach (at least half an hour before or two hours after meals). Do not chew this drug.
Recommended dosage regimen depending on body weight: - Patients weighting 60 kg or more: 400 mg once a day; - Patients weighting up to 60 kg: 250 mg once a day.
Children under 3 years old take Videx in the form of suspension. To prepare the suspension, the adult dose is dissolved in 15 ml of water. You can add apple juice without pulp in order to improve the taste of the suspension.
The daily dose for adult patients with impaired renal function depends on your body weight. Patients on dialysis should take a daily dose of Videx immediately after the procedure. It may be necessary to increase the interval between doses or reduce the dose of the drug. Elderly patients should select the daily dose more carefully. Patients with hepatic insufficiency may need a dose reduction.
What side effects may occur while using the drug?
Digestive system: anorexia, dyspepsia, nausea, vomiting, abdominal pain, diarrhea, hepatitis, hepatic insufficiency, pancreatitis, lactic acidosis, lipodystrophy.
CNS: peripheral neuropathy, paresthesia, pain in the hands and feet, headache.
Musculoskeletal system: myalgia, arthralgia, myopathy, rhabdomyolysis.
Hematopoiesis: anemia, granulocytopenia, leukopenia, thrombocytopenia.
Other reactions: dry mouth, dry eyes, optic neuritis, diabetes, alopecia, allergic reactions, asthenia, fatigue, fever, itching, skin rash.
Videx EC special instructions
Signs of residual opportunistic infections may appear in patients with severe immunodeficiency during combined antiretroviral treatment. Unwanted symptoms are observed during the first few weeks after the initiation of therapy.
The drug should be stopped with the first symptoms of pancreatitis. Pancreatitis is associated with pronounced toxic effect of the drug. This condition does not depend on the type of therapy (monotherapy or complex treatment). Nevertheless, pancreatitis can lead to death of the patient.
If the patient is on dialysis, then there is no need to change the recommended dosage regimen. The capsules should be taken after the procedure.
As for pediatrics, the recommended dosing regimen depends on the work of the patient's kidneys. The dose should be reduced in case of renal dysfunction.
Patients may need lower doses in case of hepatic dysfunction.
Videx EC interactions
Stavudine and other drugs with a similar toxicity significantly increase the risk of side effects.
Allopurinol may significantly increase the risk of pancreatitis.
Tenofovir reduces the concentration of didanosine.
Certain antibiotics (some fluoroquinolone antibiotics such as ciprofloxacin) may be less effective when used with Videx EC.
Ribavirin may increase the risk of side effects.