Truvada (tenofovir/emtricitabine) Coupons, Discounts & Cost
Truvada is a combination product with a fixed dose of emtricitabine and tenofovir disoproxil. One way to save money on the Truvada (tenofovir/emtricitabine) retail cost regardless of income and insurance status is to use Truvada (tenofovir/emtricitabine) coupons or discount cards from RXCoupons. Use our Truvada coupons at your online pharmacy and receive up to 75% off the sale price each time you refill your prescription.
Why do you need to take Truvada (tenofovir/emtricitabine)?
Truvada is a combination product with a fixed dose of emtricitabine and tenofovir disoproxil. Emtricitabine is a cytidine nucleoside analogue. Both components (emtricitabine and tenofovir) are active against human immunodeficiency virus (HIV-1). This drug is used in combination therapy with other antiretroviral agents in patients older than 18 years of age.
What are the precautions when taking Truvada (tenofovir/emtricitabine)?
Truvada contraindications: - Hypersensitivity to the active substances (tenofovir/emtricitabine) or to any other component of the drug. - Individuals under the age of 18. - Severe renal insufficiency or renal failure (if dialysis becomes necessary). - Lactation. - Combined treatment with other drugs containing tenofovir, emtricitabine or other cytidine analogues such as lamivudine. - Combined treatment with adefovir. - Patients with lactase deficiency, lactose intolerance, GGM.
Truvada should be used with extreme caution in patients with diabetes mellitus, in elderly patients (aged 65 years and over), in patients with impaired renal function.
Truvada should be avoided in patients taking other nephrotoxic medications (amphotericin B, ganciclovir, foscarnet, pentamidine, vancomycin, cidofovir), nonsteroidal anti-inflammatory drugs, HIV protease inhibitors with ritonavir or cobicistat.
Combined treatment with didanosine is not recommended.
What are the precautions during Pregnancy and lactation?
Pregnancy
No malformations or toxic effects on the fetus can be associated with emtricitabine or tenofovir. The drug does not affect the reproductive function. Thus, if necessary, Truvada may be used during pregnancy.
Breastfeeding
Studies have shown that tenofovir and emtricitabine can get into breast milk. Therefore, Truvada should not be used during breastfeeding.
In general, women infected with HIV are advised not to breastfeed in order to avoid transmission of HIV to the child.
How to use Truvada?
Take each tablet with a meal. Tablets should be swallowed whole (do not chew or crush).
Adults
The recommended dose of Truvada is 1 tablet per day. It is recommended to take the drug with food (to optimize the absorption of tenofovir).
If the patient has difficulty swallowing pills, the drug can be taken immediately after being dissolved in approximately 100 ml of water, orange or grape juice.
If Truvada dose was missed (less than 12 hours from the last dose), the patient should take this medication with food as soon as possible and return to normal scheme. If more than 12 hours has passed, the patient should not take the missed dose (return to normal scheme).
Special groups
Elderly patients
The doses for patients over the age of 65 years should not be changed (if there are no signs of renal failure).
Impaired renal function
Patients with impaired renal function should use the drug only if the potential benefit of therapy is considered to outweigh the potential risks.
Truvada is contraindicated in patients with severe violation of renal function, as well as in patients on hemodialysis.
Abnormal liver function
There is no need for dose adjustment in patients with hepatic impairment.
Children
Truvada is not recommended for children under 18 years of age.
Useful information about side effects
Possible side effects: - Headache, dizziness; - Dyspnea; - Diarrhea, nausea, vomiting, flatulence, abdominal pain, pancreatitis, indigestion; - Hyperbilirubinemia, hepatitis; - Rash, pruritus, hives, skin discoloration, other allergic reactions; - Neutropenia, anemia; - Hypophosphatemia, lactic acidosis, hypertriglyceridemia, hyperglycemia; - Insomnia, abnormal dreams; - Myopathy and osteomalacia; - Renal failure (acute and chronic), proteinuria, acute tubular necrosis, polyuria, interstitial nephritis.
Concomitant use of tenofovir and didanosine is not recommended (this may lead to severe adverse reactions).
HIV-infected patients with hepatitis B should cancel Truvada with extreme caution (cancellation may be accompanied by severe exacerbation of hepatitis).
Truvada (tenofovir/emtricitabine) special information about interactions
Truvada formulation contains tenofovir and emtricitabine. Therefore, all cases of drug interactions with these active substances are also associated with Truvada.
The drug should not be administered concomitantly with other cytidine analogues (such as lamivudine).
Truvada should not be used concomitantly with other drugs containing emtricitabine or tenofovir.
Truvada should not be administered simultaneously with Atripla, Emtriva, Viread, Combivir (lamivudine/zidovudine), Epivir (lamivudine), Hepsera (adefovir dipivoxil)