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Caverject Impulse Injection

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Caverject Impulse Injection (alprostadil) Coupons, Discounts & Cost

Alprostadil is a drug used to treat erectile dysfunction associated with neurogenic or psychogenic disorders. One way to save money on the Caverject Impulse Injection retail cost regardless of income and insurance status is to use Caverject Injection coupons or discount cards from RXCoupons. Use this Alprostadil coupon at this online pharmacy and receive up to 75% off the sale price.

Alprostadil main indications for use

Alprostadil is a drug used to treat erectile dysfunction associated with neurogenic or psychogenic disorders. It is also used in patients with chronic diseases of arteries, obliterating endarteritis, obliterating atherosclerosis, diabetic angiopathy, thromboangiitis obliterans, Reynaud's syndrome, vasculitis, systemic sclerosis.

Alprostadil dosage information

The initial dose per injection is 2.5 mcg. The dose can be increased up to 5 mcg in some patients. In most cases, a single dose of 10-20 mcg is effective. The maximum single dose is 40 mcg.

The dose is selected individually for the diagnosis of erectile function (in order to provide normal physiological response). Patients should use the dose selected by the attending physician only. The maximum frequency of injections is 2-3 times a week with an interval of at least 24 hours between injections.

Combination therapy with other drugs introduced into cavernous bodies can lead to prolonged or painful erections. Patients should avoid using Alprostadil with myotropic antispasmodics and alpha-blockers.

Obliterating diseases of peripheral arteries: 60 mcg intravenously for 2 hours.

Intermittent claudication: 40 mcg intravenously for 2 hours 2 times a day.

Atherosclerosis: 120 mcg/day intravenously.

Thromboangiitis obliterans, Reynaud's syndrome: 60 mcg intravenously for 3 hours daily.

Vasculitis, systemic sclerosis: 60 mcg for 3 hours daily.

Alprostadil should be used with caution with hypotensive and vasodilator drugs.

What are the side effects of Alprostadil?

Common side effects: pain and burning during and after injection, pain after erection, hematoma, redness, swelling, bleeding, infection of the penis. Prolonged erection (more than 4-6 hours) is very rare. Long-term treatment (up to 3 years) may lead to different penis disorders (fibrous plaque or scar).

Less common side effects: hypotension, dizziness.

Combination therapy with MAO inhibitors and in alpha-blockers may lead to hypertensive crises (sudden increase in blood pressure).

In what cases Alprostadil is contraindicated

Alprostadil is contraindicated in patients with hypersensitivity to the drug, thrombocytopenia, thrombophlebitis, venous thrombosis, urethral stricture, urethritis, penile implant. Do not use this drug in persons younger than 18 and over 75 years old.

This drug should be used only after consulting a doctor in the following cases: fibrosis of the cavernous body, Peyronie's disease (deformation during erection), sickle cell anemia, leukemia.

The drug should be administered with caution in case of ischemic heart disease, chronic heart failure, lung diseases, broncho-obstructive syndrome, liver failure, peptic ulcer, proliferative retinopathy, type 1 diabetes mellitus.

Alprostadil should not be used in patients with drug addiction or mental and intellectual disabilities.

Alprostadil is not recommended for patients with sexually transmitted diseases, as well as for patients infected with HIV.

Alprostadil at a dose of more than 20 mcg should be used with caution in patients with various disorders of the cardiovascular system.

Urgent medical supervision is recommended if the erection lasts more than 4 hours. Prolonged erection can lead to structural damage to the penis.

Special instructions for Alprostadil therapy

It is necessary to correlate the potential risks and benefits of Alprostadil therapy in patients with acute and subacute myocardial infarction, severe or unstable angina, heart failure, pulmonary edema, cardiac rhythm disturbances, arterial hypotension, bronchial obstructive syndrome, liver failure, as well as in those taking vasodilators, anticoagulants, MAO inhibitors.

Alprostadil solution for injection should be used immediately after preparation or stored for no more than 24 hours at a temperature of 2-8° C.

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