Colcrys (colchicine) Coupons, Discounts & Cost
Colcrys (colchicine) is used as a treatment for gout attacks and familial Mediterranean fever. One way to save money on the Colcrys (colchicine) retail cost regardless of income and insurance status is to use Colcrys (colchicine) coupons or discount cards from RXCoupons. Use our Colcrys (colchicine) coupons at your online pharmacy and receive up to 75% off the sale price each time you refill your prescription.
General information about Colcrys (colchicine)
Colcrys (colchicine) is used as a treatment for gout attacks and familial Mediterranean fever. It has a strong anti-inflammatory action. Colchicine activates the functioning of the digestive tract, inhibits the respiratory center, narrows blood vessels, and increases blood pressure.
Colcrys indications: Behcet's disease (anti-inflammatory action), gout (for the relief and prevention of attacks), pseudogout attacks, periodic peritonitis, systemic sclerosis (colchicine reduces dryness, irritation, softens the skin), Mediterranean fever, phlebitis (reduces inflammation), amyloidosis.
Colcrys (colchicine) contraindications
Colcrys (colchicine) is not used in hepatic and renal failure, hypersensitivity to the drug, neutropenia, serious cardiovascular pathology, disorders of brain activity, gastrointestinal disorders. It is contraindicated during pregnancy (the drug can be used only under strict indications).
Colcrys (colchicine) method of use and dosage
The recommended dosing regimen: first day: 1 tablet in the morning and 2 tablets in the evening (daily dose - 3 tablets maximum). Second and third day: 1 tablet in the morning and evening (daily dose - 2 tablets). The next day: 1 tablet in the evening (daily dose - 1 tablet). Maintenance dose in acute gouty arthritis: 1 tablet per day (in the evening). Familial Mediterranean fever: 0.5-2 tab. once daily. Amyloidosis: take from 1 to 3 tab. per day. Duration of treatment - five years. Tablets should be swallowed whole, without chewing, with a glass of water. The same dosage is used for other indications.
Colcrys (colchicine) overdose guidance
Colcrys (colchicine) overdose may cause the following symptoms: diarrhea, vomiting, stomach pain, dry skin, gastroenteritis, dehydration, hypotension, convulsions, hemoglobinuria, shortness of breath. In some patients colchicines may cause lung infiltration, hepatocellular diseases, acute renal failure, leukopenia, thrombocytopenia.
Colcrys (colchicine) unwanted side effects
Urinary system: functional disorders of the kidneys. Digestive system: diarrhea, vomiting, nausea, abdominal pain, dyspeptic symptoms (anorexia, nausea, vomiting, abdominal pain, loss of appetite, diarrhea), liver failure, vitamin B12 deficiency. Allergic reactions: rash, urticaria. Hematopoietic system: leukopenia, agranulocytosis, aplastic anemia, thrombocytopenia (during long-term treatment). Dermatologic reactions: alopecia. Other reactions: hair loss, myopathy, itching, necrosis, muscle weakness.
Colcrys (colchicine) safety information
It is recommended to systematically monitor the peripheral blood counts during treatment with Colcrys (colchicine).
The drug should not be used with alcohol (high risk of gastrointestinal toxicity, especially in patients suffering from alcoholism).
Stop using the drug or reduce the dosage in case of any serious side effects.
Colcrys (colchicine) interactions
Colcrys (colchicine) can cause unwanted effects when used with some other medications, including cyanocobalamin, macrolide antibiotics.
There were cases of severe side effects (including death) in patients taking colchicine and clarithromycin.
Verapamil may increase the concentrations of colchicines and increase the risk of side effects.
Patients with renal or hepatic impairment should not use colchicine and inhibitors of CYP3A4.
Patients with normal renal and liver function (those on simultaneous therapy with inhibitors of CYP3A4) should reduce the dose of colchicine.
Also, care should be taken while the use of antibiotics. It is not recommended to consume grapefruit and grapefruit juice during treatment with colchicine. Patients need to seek medical attention in case of symptoms such as muscle weakness, numbness or tingling in the extremities, bleeding, vomiting, nausea, fatigue.
Colcrys (colchicine) conditions of storage
Store protected from light, out of reach of children.