DDAVP spray (desmopressin) Coupons, Discounts & Cost
DDAVP spray (desmopressin) is an antidiuretic drug. Desmopressin is a synthetic analogue of vasopressin. One way to save money on the DDAVP spray (desmopressin) retail cost regardless of income and insurance status is to use DDAVP spray (desmopressin) coupons or discount cards from RXCoupons. Use our DDAVP spray (desmopressin) coupons at your online pharmacy and receive up to 75% off the sale price each time you refill your prescription.
What should patients know about DDAVP spray (desmopressin)?
DDAVP spray (desmopressin) is an antidiuretic drug. Desmopressin is a synthetic analogue of vasopressin. It has antidiuretic action. Desmopressin helps reduce the frequency of urination.
When should I use DDAVP spray (desmopressin)?
DDAVP spray (desmopressin) indications: polyuria/polydipsia, primary nocturnal enuresis, central diabetes insipidus, hemophilia of mild or moderate severity, Von Willebrand disease.
What are the contraindications for DDAVP spray (desmopressin)?
It is not recommended to use DDAVP spray (desmopressin) in patients who suffer from fluid retention in the body (of any etiology), anuria, hypersensitivity, congenital or psychogenic polydipsia, heart failure and other conditions that require diuretic therapy, hyponatremia, renal failure (mild to severe).
Desmopressin is not used in children up to 4 years (for the treatment of diabetes insipidus) and 5 years (for the treatment of primary nocturnal enuresis).
Use with caution in renal dysfunction, bladder fibrosis, fluid and electrolyte disorders, cystic fibrosis, thrombosis, increased intracranial pressure, diseases of the cardiovascular system, asthma, epilepsy and migraine.
Avoid taking the drug during pregnancy. Elderly patients (older than 65 years) should reduce the dose of the drug.
DDAVP spray (desmopressin) dosage
Desmopressin is used in the form of nasal spray. Intranasal spray: 10-40 mcg per day for adults, 5-30 mcg for children (from 3 months to 13 years). Diabetes insipidus: DDAVP spray is usually administered in a dose of 20-40 mcg per day. Children may use 10-20 mcg per day. The daily dose can be used at once or divided into several applications (depending on the efficacy and tolerability). Desmopressin optimal dose should be determined individually for each patient. Primary nocturnal enuresis: use 10-40 mcg per day. The starting dose is 20 mg per day (one dose per nostril). DDAVP spray in primary enuresis should be used at bedtime. Patients with primary nocturnal enuresis should limit their fluid intake (in the afternoon).
What are the side effects for DDAVP spray (desmopressin)?
Central nervous system: headache, dizziness, coma, emotional lability (in children). Digestive system: intestinal colic, nausea, vomiting. Cardiovascular system: mild increase in blood pressure (when used in high doses), hypotension, compensatory tachycardia. Respiratory system: rhinitis, swelling of the nasal mucosa. Urinary system: oliguria. Metabolism: hyponatremia, weight gain. Endocrine system: algomenorrhea. Allergic reactions: skin rash. Other reactions: headache, swelling. DDAVP overdose: seizures and other neurological/psychiatric symptoms, headache, drowsiness, anuria, fluid retention. Stop using DDAVP spray in case of hyponatremia.
DDAVP spray (desmopressin) additional information
Alcohol, heparin, demeclocycline, lithium, tetracycline, norepinephrine should not be used with DDAVP spray.
Carbamazepine, clofibrate, selective serotonin reuptake inhibitors, narcotic analgesics, lamotrigine, nonsteroidal anti-inflammatory drugs, tricyclic antidepressants, fludrocortisone, chlorpropamide may increase the antidiuretic effect of the drug. Loperamide may increase the absorption of desmopressin. Desmopressin increases the effects of hypertensive agents (dopamine, norepinephrine, phenylephrine, epinephrine). Cimetidine may cause bradycardia and asystole (life-threatening heart rhythm). Indomethacin may increase the intensity of action of desmopressin. Non-steroidal anti-inflammatory drugs may increase the risk of side effects. Dimethicone may reduce the absorption of desmopressin.
DDAVP spray (desmopressin) special instructions
Patients may have headache and dizziness during the period of treatment. Therefore, be careful when driving.
DDAVP spray (desmopressin) Storage conditions
Desmopressin should be kept away from children. Store the drug at room temperature.
The vial should be stored in an upright position.