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What is Dramamine (dimenhydrinate)?
Dramamine is a drug with antihistamine properties. It has strong anti-emetic effect and helps eliminate dizziness.
Dramamine (dimenhydrinate) is prescribed for symptomatic nausea, vomiting, vertigo, Meniere's syndrome, migraine, motion sickness.
The drug is well absorbed from the gastrointestinal tract. The active substance is excreted by the kidneys within 24 hours.
Dramamine (dimenhydrinate) indications for use
The drug is used to treat sea and air sickness, symptoms of vestibular and labyrinth disorders (dizziness, nausea, vomiting), except for the symptoms caused by anticancer therapy; Meniere's disease.
Dramamine (dimenhydrinate) dosing and administration
Adults: take before meals, depending on the patient's condition, at a dose of 0.05-0.1 g (1-2 tablets) 4-6 times a day. For the prevention of air and sea sickness: use 1-2 tablets half an hour before boarding a plane. Children under 6 years: the drug is given at a dose of 12.5-25 mg (1/4 or 1/2 tablets) 2-3 times a day. Children from 7 to 12 years: 25-50 mg (1/2 or 1 tablet) 2-3 times a day. Vestibular disorders: adults - 50-100 mg 2-3 times a day (the daily dose should not exceed 400 mg); children from 6 to 14 years - 25-50 mg 3 times a day (the daily dose should not exceed 150 mg).
Dramamine (dimenhydrinate) side effects
The drug may cause the following side effects: dry mouth, drowsiness, visual-perceptual disturbances. These effects usually go away when you reduce the dose. CNS: dizziness, headache, drowsiness, weakness, fatigue, impaired concentration, anxiety, nervousness, insomnia; rarely - disturbance of accommodation. Digestive system: dry mouth, decreased appetite, nausea, vomiting. Respiratory system: dry mucous membranes of the nose, thickening of bronchial secretions. Cardiovascular system: low blood pressure, tachycardia. Skin: increased sensitivity to light, rash, urticaria. Immune system: angioedema. Urinary system: urination problems. Allergic reactions: skin rash, angioedema, bronchoconstriction, dermatitis. Other: hemolytic anemia, urination problems.
Dramamine (dimenhydrinate) contraindications
Dramamine (dimenhydrinate) is contraindicated in the following conditions: hypersensitivity to the drug, epilepsy, acute herpetic and exudative dermatoses, as well as in patients under 3 years of age.
Dramamine is contraindicated during pregnancy. Women should stop breastfeeding during dimenhydrinate therapy.
Dramamine (dimenhydrinate) special instructions
Dramamine is used with caution in patients with convulsive disorders, angle-closure glaucoma, benign prostatic hyperplasia, patients with bronchial asthma, diseases of the cardiovascular system, hyperthyroidism, stenosing peptic ulcer, pyloroduodenal stenosis, bladder neck obstruction.
Patients should avoid alcohol during treatment.
Elderly patients should use the initial dose of 25 mg.
Patients with liver failure should reduce the dose.
Patients with renal failure should not reduce the dose.
Patients taking dimenhydrinate should avoid potentially hazardous activities. Dramamine may cause drowsiness, incoordination, dizziness.
Dramamine (dimenhydrinate) overdose
Symptoms: dry mouth, redness of the face, confusion; children - seizures, hallucinations. Treatment: gastric lavage, activated charcoal, symptomatic therapy.
How to use Dramamine (dimenhydrinate) during pregnancy and lactation
Dimenhydrinate is used with caution during pregnancy and lactation (breastfeeding). The drug is prescribed only when the expected therapeutic effect outweighs the potential risk of side effects. Dimenhydrinate may cause cardiovascular defects and inguinal hernia in the fetus.
Dramamine (dimenhydrinate) interaction with other drugs
Dramamine enhances the effects of atropine, tricyclic antidepressants, catecholamines, barbiturates, alcohol, sedatives and hypnotics, neuroleptics.
The drug reduces the effect of corticosteroids and anticoagulants.
The drug is not compatible with antibiotics that have ototoxic effects (streptomycin, neomycin, kanamycin, viomycin, amikacin).
Dramamine (dimenhydrinate) storage conditions
Store at temperatures below 25° C, out of reach of children.