Mildronate (meldonium) Coupons, Discounts & Cost
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Mildronate - what it is and how to use it
Mildronate (meldonium) improves metabolism and energy supply. Mildronate reduces the accumulation of toxic products and protects the cells from damage. The drug also helps quickly restore energy reserves.
Mildronate is used to treat a variety of disorders of the cardiovascular system. It also helps enhance physical and mental performance. Mildronate slows the formation of necrotic areas in acute ischemic myocardial injury. The drug increases myocardial contractility, increases tolerance and reduces the frequency of angina attacks in heart failure. Moreover, Mildronate improves blood circulation in acute and chronic ischemic cerebrovascular disorders. This drug is also used to eliminate functional disturbances of the nervous system in patients with chronic alcoholism (during abstinence syndrome).
Mildronate indications
Indications for use:
- Complex therapy of ischemic heart disease (angina, myocardial infarction), congestive heart failure;
- Complex therapy of acute and chronic cerebrovascular disorders (stroke and cerebrovascular insufficiency);
- Reduced working capacity;
- Physical stress (including stress in athletes);
- Abstinence syndrome in chronic alcoholism (in combination with specific alcoholism therapy);
- Hemophthalmus, retinal hemorrhages of different etiologies;
- Central retinal vein occlusion;
- Retinopathy of different etiology (diabetic, hypertensive retinopathy).
How to take Mildronate
It is recommended to take the drug in the morning.
Complex therapy of cardiovascular disease: the drug is prescribed at a dose of 0.5-1 g per day (1-2 times per day). The therapy lasts for 4-6 weeks.
Cardialgia associated with dishormonal cardiomyopathy: the drug is prescribed at a dose of 250 mg 2 times per day. The therapy lasts for 12 days.
Chronic cerebrovascular disorders: the drug is prescribed at a dose of 0.5-1 g per day. The therapy lasts for 4-6 weeks. Patients should repeat the course 2-3 times a year.
Mental and physical activity: the drug is prescribed at a dose of 250 mg 4 times per day. The therapy lasts for 10-14 days. If necessary, repeat the treatment after 2-3 weeks.
The recommended dose for athletes is of 0.5-1 g 2 times per day (before workouts). The therapy lasts for 14-21 days, or 10-14 days during the period of competition.
Chronic alcoholism: the drug is prescribed at a dose of 500 mg 4 times per day. The therapy lasts for 7-10 days.
Mildronate possible side effects
Cardiovascular system: rarely - tachycardia, changes in blood pressure.
CNS: rarely - psychomotor agitation.
Digestive system: rarely - symptoms of diarrhea.
Allergic reactions: rarely - skin itching, redness, rash, swelling.
Do NOT use Mildronate
Mildronate is contraindicated in the following disorders:
- Increased intracranial pressure (violation of venous outflow, intracranial tumors);
- Children and adolescents under 18 years of age;
- Hypersensitivity to the drug.
Use Mildronate with extreme caution in patients with diseases of the liver or kidneys.
Mildronate during pregnancy and breastfeeding
Mildronate should not be administered during pregnancy to avoid possible adverse effects.
If necessary, patients should stop breastfeeding during therapy.
Mildronate specific guidance
Use caution in patients with chronic liver disease and kidney failure.
The drug has low toxicity. Therefore, it does not cause side effects that are dangerous to the health.
Mildronate enhances the action of antianginal drugs, some antihypertensive drugs, cardiac glycosides. It can be combined with anticoagulants and antiplatelet agents, as well as with antiarrhythmic agents, diuretics, bronchodilators.
Nitroglycerin, nifedipine, alpha blockers, antihypertensives and peripheral vasodilators may cause mild tachycardia, hypotension (caution should be exercised when using such combinations).
The drug should be stored out of reach of children, in a dry place, at temperatures no higher than 25° C.