Plendil (felodipine) Coupons, Discounts & Cost
Plendil is a medication with antihypertensive and antianginal effects. One way to save money on the Plendil retail cost regardless of income and insurance status is to use Plendil coupons or discount cards from RXCoupons. Use this Felodipine coupon at this online pharmacy and receive up to 75% off the sale price.
Pharmacological action of Plendil
Plendil is a medication with antihypertensive and antianginal effects. The active substance (felodipine) is used to treat hypertension and stable angina.
Felodipine lowers blood pressure by reducing the total peripheral vascular resistance (especially in the arterioles). Felodipine relaxes airway smooth muscles. It has no significant effect on the concentration of lipids in the blood.
Felodipine may also be administered to patients with reduced left ventricular function, asthma, diabetes, gout, or hyperlipidemia.
Plendil effectively lowers blood pressure in hypertensive patients. Felodipine treatment may result in regression of left ventricular hypertrophy. The drug has natriuretic and diuretic effect. Felodipine reduces renal vascular resistance and increases blood flow to the kidneys. Felodipine therapy leads to improved myocardial perfusion due to dilatation of the coronary vessels. It also helps eliminate the spasm of coronary vessels.
Plendil may be used for the treatment of hypertension alone or in combination with other antihypertensive drugs (such as beta-blockers, ACE inhibitors, or diuretics). Felodipine reduces the frequency of angina attacks in patients with stable angina. As for the treatment of stable angina, felodipine may be used as monotherapy or in combination with beta-blockers.
Plendil indications:
- Arterial hypertension (as monotherapy or in combination with other antihypertensive agents, such as beta-blockers, diuretics or ACE inhibitors).
- Stable angina (as monotherapy or in combination with beta-blockers).
Plendil contraindications
Do not use Plendil in case of hypersensitivity to felodipine or other components of the drug, lactose intolerance, lactase deficiency or glucose-galactose malabsorption (this product contains lactose).
Plendil should not be used in case of heart failure, acute myocardial infarction, unstable angina. It is not for patients under 18 years of age.
Do not take Plendil if you are pregnant. Do not use in women during lactation.
Plendil should be used with care in aortic stenosis, abnormal liver function, severe renal insufficiency, heart failure after acute myocardial infarction. Use with caution in elderly patients.
Plendil dosage and administration
Take in the morning with water. Do not crush or chew the tablet. Plendil can be used on an empty stomach or with a small amount of food.
Arterial hypertension: the starting dose is 5 mg once daily. The usual maintenance dose is 5 mg once daily. If necessary, the dose may be increased. You can also use other antihypertensive agents (beta-blockers, diuretics or ACE inhibitors). The recommended maximum dose is 10 mg per day.
Angina pectoris: it is necessary to begin treatment with a dose of 5 mg once a day, and increase the dose to 10 mg once a day. Plendil may be administered in conjunction with beta-blockers.
Elderly patients: the recommended initial dose is 2.5 mg.
Impaired renal function: renal impairment does not affect the concentration of drug. However, caution should be exercised when administering the drug to patients with severe renal insufficiency.
Side effects of Plendil
The most frequent adverse reactions include swelling of the ankles (mild and moderate severity), facial flushing, headache, palpitations, dizziness, and weakness. These reactions are temporary.
Nervous system: often - headache; rarely - dizziness, paresthesia.
Cardiovascular system: often - tachycardia, palpitations, reduction of blood pressure accompanied by tachycardia; very rarely - extrasystole.
Endocrine system: very rarely - hyperglycemia.
Gastrointestinal tract: often - nausea, abdominal pain; rarely - vomiting; very rarely - gingivitis.
Skin and subcutaneous tissue disorders: rarely - urticaria, rash, itchy skin; very rarely - increased photosensitivity, leukocytoclastic vasculitis.
Musculoskeletal disorders: rarely - arthralgia, myalgia.
Kidney and urinary tract: very rarely - frequent urination.
General disorders: very often - peripheral edema; rarely - fatigue; very rarely - hypersensitivity reactions such as angioneurotic edema, swelling of the lips or tongue, fever, impotence, sexual dysfunction, chest pain, flu-like symptoms, hypotension, syncope, angina, arrhythmia.