Ranexa (ranolazine) Coupons, Discounts & Cost
Ranexa (ranolazine) is an antianginal drug used for the treatment of chronic angina pectoris. One way to save money on the Ranexa retail cost regardless of income and insurance status is to use Ranexa coupons or discount cards from RXCoupons. Use this Ranolazine coupon at this online pharmacy and receive up to 75% off the sale price.
What should I know about Ranexa?
Ranexa (ranolazine) is an antianginal drug used for the treatment of chronic angina pectoris. Ranolazine reduces the risk of angina attacks per week, regardless of the sex of the patients. The incidence of angina attacks does not increase after a sharp discontinuation of the drug. Ranexa significantly improves your exercise tolerance.
How should I use Ranexa?
The recommended initial dose of Ranexa for adults is 500 mg 2 times per day. The dose can be increased to 1000 mg 2 times per day if necessary (after 2-4 weeks). The maximum daily dose is 2000 mg. You should reduce the single dose to 500 mg if side effects occur (dizziness, nausea, or vomiting). The drug should be discontinued if unwanted symptoms do not disappear.
Titration of the dose is recommended for patients with chronic cardiac insufficiency, mild and moderate renal insufficiency, mild liver failure, as well as for patients with a body weight of less than 60 kg and elderly patients (older than 75 years).
Food does not affect the bioavailability of the drug. Therefore, Ranexa can be taken regardless of meals. Ranexa tablets should be swallowed whole, with a sufficient amount of liquid (do not crush, break and chew).
Ranexa contraindications
Ranexa is contraindicated in the following situations: - Chronic renal failure; - Hepatic insufficiency (mild or severe); - Combination therapy with itraconazole, ketoconazole, HIV protease inhibitors, clarithromycin, nefazodone; - Combination therapy with certain antiarrhythmic drugs (for example, quinidine, dofetilide); - Children and adolescents under 18 years of age; - Pregnancy; - Breastfeeding; - Lactase deficiency, hereditary lactose intolerance, glucose-galactose malabsorption syndrome; - Hypersensitivity to the components of the drug.
It is not recommended to use this drug in the following situations: - Hepatic insufficiency of mild severity; - Renal failure of mild or moderate severity; - Chronic heart failure; - Elderly patients (over 75 years); - Patients weighting less than 60 kg; - Combination therapy with diltiazem, fluconazole, erythromycin; - Combination therapy with phenytoin, phenobarbital, carbamazepine, St. John's wort; - Combination therapy with verapamil, cyclosporine.
Violations of liver function
Contraindications: hepatic insufficiency (moderate or severe).
Dose titration is recommended for patients with mild hepatic insufficiency.
Violations of kidney function
Contraindications: severe renal failure.
Dose titration is recommended for patients with mild and moderate renal failure.
Elderly patients
Dose titration is recommended for patients older than 75 years.
Patients with chronic heart failure
Dose titration is recommended for patients with chronic heart failure of moderate or severe degree. If necessary, the dose of the drug should be reduced.
Side effects of Ranexa
Side effects in patients taking Ranexa are generally mild or moderate (these usually appear during the first 2 weeks of treatment).
Nervous system: often - dizziness, headache; rarely - fainting, hypoesthesia, drowsiness, tremor, postural dizziness, amnesia, confusion, anxiety, insomnia, hallucinations.
Cardiovascular system: rarely - low blood pressure, orthostatic hypotension.
Metabolism: rarely - decreased appetite, anorexia, dehydration.
Respiratory system: rarely - dyspnea, cough, nosebleeds.
Digestive system: often - constipation, nausea, vomiting; rarely - pain in the abdomen, dyspepsia, flatulence, discomfort in the stomach, pancreatitis, erosive duodenitis, oral hypoesthesia.
Skin and subcutaneous tissues: rarely - skin itching, hyperhidrosis, allergic dermatitis, hives, skin rash, angioedema.
Musculoskeletal system: rarely - pain in the limbs, muscle spasms, swelling of the joints.
Urinary system: rarely - dysuria, hematuria, chromaturia, acute renal failure.
Reproductive system: rarely - erectile dysfunction.
General disorders: often - asthenia; rarely - fatigue, peripheral edema, thrombocytosis, weight loss, visual disorders, vertigo, tinnitus, hearing loss.
Overdose symptoms: dizziness, nausea and vomiting, diplopia, fainting.
Treatment: symptomatic therapy.
Special instructions
The drug should be stored out of reach of children at a temperature of no higher than 25° C.