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Lozol (indapamide) Coupons, Discounts & Cost

Lozol (indapamide) is a drug with hypotensive, diuretic and vasodilating effect. One way to save money on the Lozol retail cost regardless of income and insurance status is to use Lozol coupons or discount cards from RXCoupons. Use this Indapamide coupon at this online pharmacy and receive up to 75% off the sale price.

What is Lozol?

Lozol (indapamide) is a drug with hypotensive, diuretic and vasodilating effect. Indapamide is indicated for the treatment of hypertension.

Lozol is contraindicated in patients with severe renal failure (anuria), severe hepatic impairment (including encephalopathy), galactosemia, hypokalemia, glucose-galactose malabsorption, lactose intolerance, hypersensitivity to sulfonamide derivatives. The drug is not used during pregnancy and lactation, as well as in patients under 18 years of age.

Indapamide should be taken with caution in patients with functional disorders of the kidney or liver disease, diabetes, hyperuricemia, disorders of water and electrolyte balance, hyperparathyroidism. Patients receiving other anti-arrhythmic drugs should also avoid Lozol.

What should I know about Lozol administration and dosage?

Indapamide is taken orally, once in the morning, with a sufficient quantity of liquid. The daily dose is 1 tablet (2.5 mg). If there is no desired therapeutic effect after 1-2 months of therapy, it is not recommended to increase the dose (high risk of side effects). In these cases, your regimen should include other antihypertensive drug (not a diuretic). Indapamide dose should not be changed if you receive two different preparations.

What should I know about Lozol side effects?

Some of the side effects that can occur with Lozol:

Digestive system: abdominal pain, nausea, dry mouth, anorexia, vomiting, gastralgia, diarrhea, constipation, hepatic encephalopathy; rarely - pancreatitis.

Cardiovascular system: orthostatic hypotension, arrhythmia, hypokalemia, palpitations.

Central nervous system: nervousness, fatigue, headache, drowsiness, dizziness, insomnia, vertigo, depression; rarely - malaise, weakness, muscle spasms, irritability, anxiety.

Urinary system: nocturia, frequent infections, polyuria.

Respiratory system: sinusitis, pharyngitis, cough; rarely - rhinitis.

Hematopoietic system: rarely - leukopenia, thrombocytopenia, agranulocytosis, hemolytic anemia, bone marrow aplasia.

Other systems: hypercalcemia, hyperuricemia, hypokalemia, hyperglycemia, hyponatremia, hyposalemia, glycosuria, hypercreatininemia, systemic lupus erythematosus.

Allergic reactions: hemorrhagic vasculitis, urticaria, rash, pruritus.


Symptoms include nausea, vomiting, weakness, functional gastrointestinal disorders, water-electrolyte imbalance, respiratory depression. Patients with cirrhosis: hepatic coma.

Treatment: gastric lavage, symptomatic therapy.


Elderly patients and patients taking laxatives and cardiac glycosides should use Lozol with caution. Hypercalcemia associated with indapamide therapy may mask the symptoms of undiagnosed hyperparathyroidism. It is necessary to control blood glucose levels in diabetic patients (especially in those with hypokalemia).

Dehydration can cause acute renal failure: patients should carefully monitor renal function, especially at the beginning of treatment.

Derivatives of sulfonamides may cause exacerbation of systemic lupus erythematosus. In some cases, Lozol therapy may lead to individual reactions, which are associated with blood pressure changes (especially at the beginning of therapy, or with another antihypertensive agent).

What should I know about Lozol interactions?

Combined therapy with some medicines may lead to undesirable effects:

- Saluretics, laxatives, cardiac glycosides, glucocorticoids, mineralocorticoids, amphotericin B increase the risk of hypokalemia; - Erythromycin (intravenously), astemizole, pentamidine, vincamine, terfenadine, sultopride, disopyramide, quinidine, amiodarone, sotalol may cause arrhythmia; - Nonsteroidal anti-inflammatory drugs, steroids, sympathomimetics may reduce the antihypertensive effect of Lozol; - Calcium may cause hypercalcemia; - Antipsychotics and tricyclic antidepressants increase the hypotensive effect and the risk of orthostatic hypotension; - Cyclosporine increases the risk of hypercreatininemia; - Metformin increases the risk of lactic acidosis; - Iodine-based contrast agent administration (in high doses) may lead to renal dysfunction; - Baclofen may increase the antihypertensive effect of Lozol; - Potassium-sparing diuretics may cause hyper- or hypokalemia (particularly in patients with renal insufficiency and diabetes).

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