Motilium (domperidone) Coupons, Discounts & Cost
Motilium (domperidone) is an antiemetic drug used for the treatment of gastrointestinal diseases. One way to save money on the Motilium retail cost regardless of income and insurance status is to use Motilium coupons or discount cards from RXCoupons. Use this Domperidone coupon at this online pharmacy and receive up to 75% off the sale price.
Motilium pharmacological action
Motilium (domperidone) is an antiemetic drug used for the treatment of gastrointestinal diseases. The active substance of Motilium - domperidone - is a stimulant of intestinal peristalsis. Unlike most antipsychotic drugs, domperidone does not cause extrapyramidal side effects (parkinsonism, dystonia, tremor, chorea, athetosis, akathisia, myoclonus). Domperidone also stimulates prolactin production.
Domperidone increases the probability of antral and duodenal contractions and accelerates gastric emptying in healthy people. Domperidone has no effect on gastric secretion.
Motilium: indications for use
Motilium (domperidone) is prescribed for dyspeptic disorders caused by delayed gastric emptying, reflux, esophagitis (vomiting, bloating, heartburn, nausea, epigastric pain). The drug is also used to treat nausea, vomiting (provoked by dopamine agonists), nausea and vomiting caused by radiation therapy. The treatment is helpful for patients suffering from Parkinson's disease.
Motilium is effective for children - in case of vomiting, gastroesophageal reflux, digestive motility disorders.
Motilium (domperidone) should not be used in case of gastrointestinal perforation, pituitary tumors, gastrointestinal bleeding, as well as in case of hypersensitivity to the active substance of the drug.
Motilium should not be used simultaneously with ketoconazole, erythromycin, voriconazole, fluconazole, amiodarone, clarithromycin, telithromycin. It is not recommended to use this drug during lactation or pregnancy.
Motilium: instructions for use
It is recommended to take the drug before meals (food can slow down the absorption of domperidone).
Dyspeptic symptoms: children and adults should take 10mg 3 times a day for 15-30 min before meals. The maximum dose is 80 mg per day. Adults may double the dosage if necessary.
Motilium suspension (for children) is used at a dose of 2.5 ml per 10 kg body weight. Children older than 1 year may double the dosage if necessary. The maximum dose is no more than 80 mg per day.
Treatment of vomiting and nausea: children (older than 12 years) and adults should take 20mg 3-4 times per day before meals. The maximum dose is 80 mg per day.
Patients with renal failure should be under close clinical observation (longer time intervals between doses needed).
Motilium: side effects
Motilium (domperidone) may cause amenorrhea, hyperprolactinemia (increased levels of prolactin), gynecomastia, reversible extrapyramidal symptoms in children, disorders of the gastrointestinal tract, allergic reactions. Motilium may cause neurological disorders in children under one year of age.
Digestive system: gastrointestinal disorders, stomach cramps (very rarely).
Nervous system: extrapyramidal symptoms, drowsiness, headache.
Psychiatric disorders: agitation, nervousness (very rarely). Such side effects are rare and occur mainly in children and infants.
Endocrine system: high prolactin levels, galactorrhea, gynecomastia and amenorrhea.
Immune system: anaphylactic reactions, including anaphylactic shock, angioedema, allergic reactions, urticaria (very rarely).
Skin disorders: itching, rash (very rarely).
Motilium overdose symptoms may include disorientation, drowsiness, extrapyramidal disorders (in children).
Motilium: special instructions
Do not take Motilium with antacids or antisecretory drugs (they should be taken after meals, i.e. should not be taken simultaneously with Motilium).
Motilium suspension contains sorbitol; therefore it should not be used in patients with sorbitol intolerance.
Motilium should be used with caution in patients with hepatic insufficiency.
Patients on long-term therapy should be regularly monitored.
Motilium can be used with neuroleptics and dopamine receptor agonists (bromocriptine, levodopa).
Motilium has no or little effect on the skills involved in automobile driving.